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OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
Bone loss in elderly males is associated with a high mortality rate because of fracture. A growing body of evidence indicates that low androgen levels are linked with bone loss in elderly men, suggesting that the regulatory role of androgen in aged male bones deserves more attention, and it is not e...
ORGANISM(S): Mus Musculus 
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation
ORGANISM(S): Homo Sapiens (human) 
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