Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
Proteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via liquid chromatography–mass spectrometry (LC-MS), highlighting the expected LPS-induced increase in accumulation of proteases, ribonucleases (RNase) and other hydrolases.
To gain a deeper insight into the residual SARS-CoV-2 peptides after degradation, we directly detected fragments (lower than 10 (kilodalton) kDa) of degraded SARS-CoV-2 via LC-MS, and overlapped these with the 3D crystal structure of SARS-CoV-2 proteins.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2
