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UnknownCytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.
Not available
S-EPMC3281628 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Altered Expression of miRNAs and piRNAs in the Testes of Mtdh exon 3-deficient Mice
Purpose: To identify the correlation of the expression of testicular miRNAs and piRNAs with the infertility of Mtdh exon 3 deficient mice Methods: Total RNAs from individual testis of two WT mice and three homozygous Mtdh exon 3-depleted mice were used to prepare the miRNA sequencing library. After ...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-62330 | biostudies-arrayexpress
UnknownKnockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Not available
S-EPMC3110819 | biostudies-literature
UnknownGenetic Deficiency of Mtdh Gene in Mice Causes Male Infertility via Impaired Spermatogenesis and Alterations in the Expression of Small Non-coding RNAs.
Not available
S-EPMC4424326 | biostudies-literature
TranscriptomicsExpression data from MTDH knockdown in the Hec50co endometrial cancer cell line
Understanding the molecular underpinnings of chemoresistance is vital to design therapies to restore chemosensitivity. In particular, metadherin (MTDH) has been demonstrated to have a critical role in chemoresistance. Over-expression of MTDH has recently been implicated in poor clinical outcome in b...
ORGANISM(S): Homo sapiens 
2010-12-17 | E-GEOD-26134 | biostudies-arrayexpress
UnknownMetadherin enhances vulnerability of cancer cells to ferroptosis.
Not available
S-EPMC6746770 | biostudies-literature
UnknownExpression data from MTDH knockdown in the Hec50co endometrial cancer cell line
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-26134 | biostudies-other
UnknownMTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.
Not available
S-EPMC6825893 | biostudies-literature
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