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Proteomicsproteomic profiling of human meniscus
There is a need to clarify the role of the meniscus in knee OA which may be aided by the identification of biomarkers that reflect the molecular events involved in the tissue degradation. This is of particular importance in the early stages of the degenerative processes, a crucial phase when it migh...
ORGANISM(S): Homo sapiens (Human) 
2024-04-03 | PXD042122 | Pride
Osteoarthritis Meniscus Human 
ProteomicsSimulated microgravity inspired osteoarthritis model reveals CD36 as a sex dimorphic drug target
Osteoarthritis (OA) is a prevalent and debilitating disease that predominantly affects load-bearing joints (1). Knee osteoarthritis (KOA) is characterized by the progressive degradation of nearly all structures within the knee joint, leading to pain, stiffness, and reduced joint mobility (2-4). The ...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-27 | PXD064341 | Pride
Meniscus 
TranscriptomicsSingle-Cell RNA Sequencing Reveals the Cellular and Molecular Characterization of Discoid Meniscus
Discoid meniscus is a morphological abnormality with a higher prevalence in Asian populations (15%-20%) compared to American populations (3%-5%). Although most patients are asymptomatic, discoid meniscus are more susceptible to injury than normal menisci. Currently, our understanding of its pathogen...
ORGANISM(S): Homo sapiens 
2025-07-09 | E-MTAB-15232 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Injured Meniscus Reveals a Distinct Phenotype of Meniscus Degeneration with Aging
In this study, we have tested the variation in gene expression signatures in human injured meniscus with age and degree of chondrosis in the knee. We found several genes that were differentially regulated with each of these factors and they represent important biological pathways in osteoarthritis r...
ORGANISM(S): Homo sapiens 
2013-03-18 | E-GEOD-45233 | biostudies-arrayexpress
GenomicsSingle-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration
Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration
PRJNA551470 | ENA
GenomicsMeniscus Gene Expression Profiling: Inner and Outer Zone Tissue Comparison to Cartilage and Passaged Monolayer Meniscus Cells
Meniscus Gene Expression Profiling: Inner and Outer Zone Tissue Comparison to Cartilage and Passaged Monolayer Meniscus Cells
PRJNA1149299 | ENA
GenomicsSingle cell-seq identify discoid lateral meniscus
Single cell-seq identify discoid lateral meniscus
PRJNA682995 | ENA
GenomicsMeniscus-On-a-Chip model to delineate multi-tissue crosstalk
Meniscus-On-a-Chip model to delineate multi-tissue crosstalk
PRJNA1402394 | ENA
GenomicsMechano-Hypoxia Conditioning of Engineered Human Meniscus
Mechano-Hypoxia Conditioning of Engineered Human Meniscus
PRJNA748371 | ENA
TranscriptomicsRNA-seq of CD146-positive vs CD146-negative cells isolated from human meniscus
This study aims to characterize the transcriptomic differences between CD146-positive and CD146-negative cells isolated from human meniscus tissues. Meniscus tissue samples were collected from total knee arthroplasty (TKA) patients lacking significant joint space narrowing. CD146-positive and CD146-...
ORGANISM(S): Homo sapiens 
2026-08-31 | E-MTAB-17450 | biostudies-arrayexpress
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