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TranscriptomicsSeminal plasma exposures strengthen vaccine responses in the female reproductive tract mucosae
HIV-1 sexual transmission occurs mainly via mucosal semen exposures. In the female reproductive tract (FRT), seminal plasma (SP) induces physiological modifications, including inflammation. An effective HIV-1 vaccine should elicit mucosal immunity. However, modifications of vaccine responses by the ...
ORGANISM(S): Macaca fascicularis 
2019-02-12 | E-MTAB-7639 | biostudies-arrayexpress
TranscriptomicsModified Vaccinia virus Ankara vector induces specific cellular and humoral responses in the female reproductive tract, the main HIV portal of entry
The female reproductive tract is one of the major mucosal invasion site of HIV-1. This site has been neglected in previous HIV-1 vaccine studies. Immune responses in the female reproductive tract after systemic vaccination remain to be characterized. Using a modified vaccinia virus Ankara (MVA) as a...
ORGANISM(S): Macaca fascicularis 
2017-06-09 | E-MTAB-5663 | biostudies-arrayexpress
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