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TranscriptomicsSingle-cell immune repertoire sequencing of bone marrow plasma cells following infection and immunizations
We performed single-cell transcriptome and antibody repertoire sequencing of bone marrow plasma cells following protein (OVA and TNFR2) immunizations or infection with high dose LCMV clone 13.
ORGANISM(S): Mus musculus 
2021-12-01 | E-MTAB-11096 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis to evaluate the function of USP18 in the mouse CNS
Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis, and as such they are crucially important for organ integrity. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, calle...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-61499 | biostudies-arrayexpress
TranscriptomicsThe alarmin interleukin-33 drives protective antiviral CD8+ T cell responses
Pathogen-associated molecular patterns decisively influence antiviral immune responses, whereas the contribution of endogenous signals of tissue damage, also known as “damage-associated molecular patterns” or “alarmins”, remains ill-defined. We show that interleukin-33 (IL-33), an alarmin released f...
ORGANISM(S): Mus musculus 
2012-02-27 | E-GEOD-34392 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis to evaluate the role of USP18 in primary microglia and the microglia cell line BV-2
Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis, and as such they are crucially important for organ integrity. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, calle...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-61500 | biostudies-arrayexpress
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