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TranscriptomicsWhole transcriptome sequencing reveals dynamic RNA changes in the aging rat brain
Using RNA-seq, 9 cerebral cortex RNA samples were sequenced from 6 month (n=3, 6 individuals pooled), 12 month (n=3, 6 individuals pooled) and 28 month (n=3, 6 individuals pooled) rats. Allowing brain aging in the cerebral cortex to be assessed. Transcriptional profiling of the ageing cerebral corte...
ORGANISM(S): Rattus norvegicus 
2012-05-09 | E-GEOD-34272 | biostudies-arrayexpress
TranscriptomicsThe global gene expression profile of superficial zone articular cartilage in P1 wildtype and Prg4 transgenic mice
To examine the unbiased global gene expression of over-expression of Prg4 in superficial zone articular chondrocytes in mice. This approach allows us to define novel signaling changes caused by the over-expression of Prg4 in superficial zone articular chondrocytes Total RNA was isolated from superf...
ORGANISM(S): Mus musculus 
2013-06-24 | E-GEOD-43663 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging
Using RNA-seq, 39 cerebral cortex RNA samples were sequenced. The study design was as follows: Ad libitum fed rats at 6 months (n=3, 6 individuals pooled), 12 months (n=3, 6 individuals pooled) and 28 months (n=3, 6 individuals pooled). Calorie restricted rats at 6 months (n=3, 6 individuals poole...
ORGANISM(S): Rattus norvegicus 
2015-11-22 | E-GEOD-57110 | biostudies-arrayexpress
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
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