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TranscriptomicsLarge scale screening for fusion genes in sarcoma patient samples
We have utilized our custom array GPL11054 to screen a set of sarcoma patient samples for fusion genes One negative control was included in the study. We wanted to investigate the power of our fusion-gene array GPL11054 as a means for fusion gene detection in a series of sarcoma patient samples from...
ORGANISM(S): Homo sapiens 
2013-10-23 | E-GEOD-43632 | biostudies-arrayexpress
TranscriptomicsRetained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma (Expression)
Global gene expression analysis of inflammatory leiomyosarcoma (ILMS) and conventional leiomyosarcoma (LMS). RNA was extracted from frozen tumor biopsies (3 ILMS and 15 LMS) and hybridized onto Affymetrix Human Gene 1.0 ST arrays. LMS_18b is the same sample as LMS_18a, analyzed at a different time p...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-37992 | biostudies-arrayexpress
TranscriptomicsRetained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma (Illumina)
Inflammatory leiomyosarcoma (ILMS) is a soft tissue tumor that morphologically resembles conventional leiomyosarcoma (LMS) admixed with a prominent inflammatory infiltrate. Genetic data on ILMS are still limited but have suggested that this entity is characterized by hyperhaploidy (24-34 chromosomes...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38015 | biostudies-arrayexpress
TranscriptomicsConcomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma
Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor ...
ORGANISM(S): Homo sapiens 
2010-11-24 | E-GEOD-19040 | biostudies-arrayexpress
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