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no omics definedTranscription profiling by array of mouse Col8a1-Col8a2 deficient and wild type mesangial cells stimulated with TGF-beta1
Col8a1/Col8a2-deficient mesangial cells and wildtype cells are treated with TGFbeta-1 for 24h. This experiment was replicated once.
ORGANISM(S): Mus musculus 
2011-01-01 | E-MEXP-2658 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of high-glucose stimulated human mesangial cells and tubular epithelial cells
we performed genome-wide transcriptome profiling in mesangial cells and tubular epithelial cells (TECs), which were stimulated by high glucose (HG) and detected the expression of inflammation associated genes. HG increased the mRNA expression of oxidative stress, inflammasome and mammalian target of...
ORGANISM(S): Homo sapiens 
2013-12-16 | E-GEOD-52734 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary mesangial cells stimulated with DNA and RNA ligands
Extrarenal viral infections commonly trigger glomerulonephritis mostly in association with immune complex disease. The immunoglobulin component of immune complexes can activate glomerular cell Fc receptors but whether complexed viral nucleic acids contribute to glomerular inflammation remains unknow...
ORGANISM(S): Mus musculus 
2008-10-21 | E-GEOD-11898 | biostudies-arrayexpress
TranscriptomicsHeme oxygenase-1 knocked down rat mesangial cells treated with hydrogen peroxide
HO-1 cells denote the cultured rat mesangial cells with heme oxygenase-1 knocked down by RNA interference (using lentiviral vector). GFP cells denote the cultured rat mesangial cells that are transfected with empty lentiviral vector containing GFP cassette. Cells are treated with hydrogen peroxide 1...
ORGANISM(S): Rattus norvegicus 
2014-01-10 | E-GEOD-53953 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mesangial cell line MES-13 to examine the global effects of high glucose (HG) and glucosamine (GlcN) on the transcriptome.
The renal mesangial cells play an important role in the development of diabetic glomerulosclerosis and renal failure. We have previously demonstrated some of the effects of high glucose are mediated via the hexosamine biosynthesis pathway (HBP) in which fructose-6-phosphate is converted to glucosami...
ORGANISM(S): Mus musculus 
2007-12-01 | E-GEOD-2557 | biostudies-arrayexpress
TranscriptomicsTranscriptomic and proteomic profiling reveal insights of mesangial cell function in patients with IgA Nephropathy
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The disease is characterized by galactose deficient IgA (gd-IgA) in the circulation forming immune complexes. The complexes are deposited in the glomerular mesangium leading to inflammation and loss of renal function, but the...
ORGANISM(S): Homo sapiens 
2017-07-03 | E-GEOD-93798 | biostudies-arrayexpress
TranscriptomicsMicroarray expression data from human renal mesangial cells (HMC) treated with a Cyclosporine A (CsA) time course.
HMCs were treated with CsA (4.2 M-BM-5M) for 0 12 and 48 hours. To exmaine global gene changes in the renal mesangium following CsA treatment in order to identify novel contributors to CsA-induced renal dysfunction Microarray analysis was used to identify novel mechanisms of CsA nephrotoxicity in th...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30952 | biostudies-arrayexpress
ProteomicsComparative analysis of commercial human primary mesangial cell, implications for experimental design.
Research on human glomerular mesangial cells (MCs) is mainly performed in vitro on primary MCs. Commercially available MCs originate from different donors and thus, because of their origin, the outcome of the experiments could potentially be affected. We have compared two commercially available pr...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD060148 | Pride
Pdgf-bb primary human mesangial cells mesangium glomerulus Quantitative proteomics 
TranscriptomicsComparison of gene expression between caveolin-1 wild-type and knockout mouse mesangial cells
To identify effects of caveolin-1 deletion on gene expression in kidney mesangial cells.
ORGANISM(S): Mus musculus 
2019-05-25 | E-MTAB-7913 | biostudies-arrayexpress
GenomicsTranscriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells
PRJNA591452 | ENA
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