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MetabolomicsOrganotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations
BACKGROUND: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation; this harsh microenvironment promotes genomic in...
2019-02-08 | MTBLS669 | MetaboLights
MetabolomicsTranscriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models

Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavourable conditions. Quiescent cells are characterized by slow or non-proliferation and deep down-regulation of processes related to biosynthesis. Although quiescence has been described mostly...

2022-02-23 | MTBLS4046 | MetaboLights
MetabolomicsImmunomodulatory activity of hyaluronidase is associated with metabolic adaptations during acute inflammation
Not available
ORGANISM(S): Mus musculus 
ST001255 | MetabolomicsWorkbench
MetabolomicsComparative metabolomics analysis reveals high-altitude adaptations in a toad-headed viviparous lizard, Phrynocephalus vlangalii
Extreme environmental conditions at high altitude, such as hypobaric hypoxia, low temperature, and strong UV radiation, pose a great challenge to the survival of animals. Although the mechanisms of adaptation to high-altitude environments have attracted much attention for native plateau species, the...
2024-01-16 | MTBLS6900 | MetaboLights
MetabolomicsMulti-Omics profiling reveals immunometabolic adaptations underlying disease resilience in indigenous Lueyang Silky Fowl compared to White Leghorns
Sustainable avian production demands genetic strategies beyond vaccines to enhance disease resilience, particularly in indigenous breeds like Lueyang Silky Fowl (LSF), which show superior resistance compared to commercial White Leghorn chickens (WLC) but lack molecular characterization. We hypothesi...
2026-05-27 | MTBLS14590 | MetaboLights
MetabolomicsMetabolic Adaptations to Chronic and Acute Exercise in Overweight Adults (ATX-Study) preliminary data
Not available
ORGANISM(S): Homo sapiens 
ST000777 | MetabolomicsWorkbench
MetabolomicsIdentifying metabolic adaptations characteristic of multiple myeloma cells via amino acids concentrations from bone marrow plasma
Not available
ORGANISM(S): Homo sapiens 
ST000791 | MetabolomicsWorkbench
MetabolomicsIdentifying metabolic adaptations characteristic of multiple myeloma cells via mass spectrometry-based metabolite profiling from Peripheral Plasma
Not available
ORGANISM(S): Homo sapiens 
ST000787 | MetabolomicsWorkbench
MetabolomicsIdentifying metabolic adaptations characteristic of multiple myeloma cells via targeted sphingolipids concentrations from bone marrow and peripheral plasma
Not available
ORGANISM(S): Homo sapiens 
ST000790 | MetabolomicsWorkbench
MetabolomicsIdentifying metabolic adaptations characteristic of multiple myeloma cells via mass spectrometry-based metabolite profiling from Bone Marrow Plasma
Not available
ORGANISM(S): Homo sapiens 
ST000788 | MetabolomicsWorkbench
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