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MetabolomicsStable isotope labelling of Toxoplasma gondii under iron and copper restriction

Toxoplasma uses metal nutrients like iron and copper for vital functions in their energy metabolism. Here, we have used stable isotope labelling to track the incorporation of glucose and glutamine into metabolic pathways, primarily focusing on central carbon metabolism, when these metals are disr...

2026-03-18 | MTBLS13492 | MetaboLights
Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
Proteomicsyeast membrane proteomics using Leu3 labelling
The yeast signal peptide peptidase homologue Ypf1 functionally interacts with the ER-associated degradation (ERAD) factors Dfm1 and Doa10 to control the abundance of the zinc transporter Zrt1. Here we report that Ctr1 is another substrate for this degradation mechanism with deletion of Ypf1 leading ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-04-12 | PXD003052 | Pride
Proteomics Erad Leu3 labelling Yeast Membrane 
MetabolomicsDivergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition
Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense. In comparison to the well-studied T. brucei, there is a major paucity of knowledge regarding the biology of T. congole...
2021-07-20 | MTBLS2372 | MetaboLights
ProteomicsLipid-specific metabolic labelling reveals site-specific heterogeneity in long-chain S-acylation
Long-chain S-acylation is a post-translational modification that regulates key cellular processes, including signal transduction and metabolic regulation. However, the dynamic nature, and site- and lipid-specific patterns of long-chain protein acylation remain poorly understood. Site- and lipid-spec...
ORGANISM(S): Homo sapiens (Human) 
2026-06-30 | PXD066568 | Pride
Liquid chromatography Tandem mass spectrom-etry Lipid metabolic labelling Long-chain s-acylation 
MetabolomicsThe diversity of quinoa morphological traits and seed metabolic composition

Quinoa (Chenopodium quinoa Willd.) is an herbaceous annual crop of the amaranth family (Amaranthaceae). It is increasingly cultivated for its nutritious grains, which are rich in protein and essential amino acids, lipids, and minerals. Quinoa exhibits a high tolerance towards various abi...

2022-03-10 | MTBLS2382 | MetaboLights
TranscriptomicsMetabolic syndrome exercise training
We assessed vastus lateralis muscle gene expression levels of 12 women with the metabolic syndrome before and after a 6 month exercise training program RNA was isolated from a vastus lateralis muscle biopsy of 6 women with the metabolic syndrome before and after a 6 month guided endurance exercise t...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-43760 | biostudies-arrayexpress
MetabolomicsLysine acetyltransferase Rv0998 coordinates transcriptional and metabolic adaptation of Mycobacterium tuberculosis to acidic pH

Mycobacterium tuberculosis (Mtb) survives host defences by adapting to host conditions, including acid stress, during infection. A critical survival strategy involves pH homeostasis, mediated by complex signalling systems that regulate metabolic reprogramming and stress responses. While ...

2026-09-03 | MTBLS15171 | MetaboLights
GenomicsiTag labelling of Liver, Plasma and VsWAT RNA
iTag labelling of Liver, Plasma and VsWAT RNA
PRJNA600955 | ENA
GenomicsiTag labelling of Liver, Plasma and VsWAT RNA
iTag labelling of Liver, Plasma and VsWAT RNA
PRJNA551493 | ENA
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