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MetabolomicsMetabolomic changes in Mycobacterium avium subsp. paratuberculosis (MAP) challenged Holstein-Friesian cattle suggest the role of serum amino acids as indicators of immune system activation

INTRODUCTION: Paratuberculosis, commonly known as Johne’s disease, is a chronic intestinal infection of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). Clinical signs, including reduced milk yields, weight loss and diarrhoea, are typically abse...

2022-02-23 | MTBLS2963 | MetaboLights
MetabolomicsMap of microbially induced metabolic changes across diverse body sites in mice - Mouse Data
Not available
ORGANISM(S): Mus musculus 
ST002465 | MetabolomicsWorkbench
MetabolomicsMap of microbially induced metabolic changes across diverse body sites in mice - Bacterial culture data
Not available
ORGANISM(S): Several mouse commensals 
ST002289 | MetabolomicsWorkbench
MetabolomicsA metabolic map of the DNA damage response identifies PRDX1 in nuclear ROS scavenging and aspartate synthesis
Not available
ORGANISM(S): Homo sapiens 
ST002234 | MetabolomicsWorkbench
TranscriptomicsTranscription map of wheat chromosome 3B
To improve our understanding of the organization and regulation of the wheat gene space, we established the first transcription map of a wheat chromosome (3B) by hybridizing the newly developed INRA GDEC Triticum aestivum NimbleGen 12x40k unigenes microarray with BAC pools from a new version of the ...
ORGANISM(S): Triticum aestivum 
2011-11-03 | E-TABM-1095 | biostudies-arrayexpress
TranscriptomicsDifferentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line
Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro THP-1 (ATCC TIB-202) cell line infection, comparing bacteria grown in host medium and intracellular bacteria recovered from infected THP-1 cells. Two-condition experiment, MAP-K vs. intracellular MAP-THP-1. Biolog...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2012-05-31 | E-GEOD-32242 | biostudies-arrayexpress
ProteomicsMetabolomics and Lipidomics Screening Reveal Reprogrammed Signaling Pathways toward Cancer Development in Non-Alcoholic Steatohepatitis
Non-alcoholic fatty liver disease is now considered the most common form of chronic liver disease. It is a complex metabolic disease that silently progresses into non-alcoholic steatohepatitis (NASH). In fact, NASH is the tipping point for pericellular fibrosis, cirrhosis and hepatocellular carcinom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-08-19 | MSV000088003 | MassIVE
TranscriptomicsInter- and intra- chromosomal interactions change on a global scale according to the metabolic regime employed by Saccharomyces cerevisiae
Nuclear and mitochondrial organelles must maintain a communication system. Loci on the mitochondrial genome were recently reported to interact with nuclear loci. To determine whether this is part of a DNA based communication system we used genome conformation capture to map the global network of DNA...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-17 | E-GEOD-33074 | biostudies-arrayexpress
MetabolomicsIntra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type-2 diabetes
In this study we explored a unique cohort of 43 samples to build a map of metabolites varying in T2D across five different tissues (subcutaneous adipose tissue, liver, pancreatic islets, skeletal muscle and blood serum). The samples originate from the Excellence in Diabetes biobank (EXODIAB) in Swed...
2018-10-08 | MTBLS690 | MetaboLights
TranscriptomicsA transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype
This SuperSeries is composed of the following subset Series: GSE18583: Baseline skeletal muscle gene expression GSE35659: A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype (resting muscle after endurance training) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-35661 | biostudies-arrayexpress
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