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MetabolomicsSex-specific metabolic shifts in plasma of COVID-19 patients after cure
Metabolic profiling in COVID-19 patients has been associated with disease severity, but there is no report on sex-specific metabolic changes in discharged survivors. Herein we used an integrated approach of LC-MS-and GC-MS-based untargeted metabolomics to analyze plasma metabolic characteristics in ...
2022-01-10 | MTBLS2224 | MetaboLights
MetabolomicsHost Tree and Geography Induce Metabolic Shifts in the Epiphytic Liverwort Radula complanata
Bryophytes are prolific producers of unique, specialized metabolites that are not found in other plants. As many of these unique natural products are potentially interesting, for example, pharmacological use, variations in the production regarding ecological or environmental conditions have not ofte...
2026-01-29 | MTBLS6740 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (GC-MS assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS288 | MetaboLights
MetabolomicsRapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster
Metabolites are active controllers of cellular physiology, but their role in complex behaviors is less clear. Here we report the metabolic changes that occur during the transition between hunger and satiety in Drosophila melanogaster. To analyze these data in the context of fruit fly metabolic netwo...
2019-07-13 | MTBLS180 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS neg assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS287 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS pos assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS286 | MetaboLights
MetabolomicsMetabolomic homeostasis shifts after callus formation and shoot regeneration in tomato
Plants can regenerate from a variety of tissues on culturing in appropriate media. However, the metabolic shifts involved in callus formation and shoot regeneration are largely unknown. The metabolic profiles of callus generated from tomato (Solanum lycopersicum) cotyledons and that of shoot regener...
2018-06-29 | MTBLS447 | MetaboLights
MetabolomicsHeat drives tomato bacterial wilt through enhanced pathogen virulence and rhizosphere microbiome and metabolic shifts
Bacterial wilt caused by Ralstonia solanacearum is globally widespread and strongly associated with elevated temperature, yet the ecological mechanisms underlying temperature-driven disease outbreaks remains unclear. Here, we show that high temperature promotes bacterial wilt by reconfiguring the to...
2026-05-31 | MTBLS14437 | MetaboLights
MetabolomicsInhibition of jasmonic acid-isoleucine conjugating enzyme JAR1 shifts the local and systemic leaf signals and metabolic profiles in Arabidopsis

• Jasmonates (JAs)-mediated pathways are central signaling hubs in plant defense responses. However, the identification of mobile and non-mobile signals involved in downstream systemic signaling is still less studied.

• Here, we investigate the role of the jasmonic acid-isoleucine conjugati...

2026-03-31 | MTBLS14117 | MetaboLights
MetabolomicsCoupled nitrogen fixation and substrate stabilization drive ecological strategy shifts during microbial succession

Background:

Primary succession is predicted to proceed through shifts from stress-tolerant to competitive to cooperative ecological strategies as resource availability increases, yet molecular evidence for these transitions in microbial systems remains limited. Here, we used an integrated m...

2026-03-12 | MTBLS14041 | MetaboLights
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