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ProteomicsRelease of the plant peptide hormone PEP1 from its precursor PROPEP1 in response to physical damage is due to Ca2+-dependent activation of METACASPASE4.
Physical damage to cells leads to the release of immunomodulatory peptides in order to elicit wound defense responses in the surrounding tissue. In Arabidopsis thaliana, the intracellular PROPEP1 protein precursor is processed into the mature 2.5 kDa PEP1 before release. However, the maturation mech...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-18 | PXD010816 | Pride
Arabidopsis Protease Metacaspase4 Proteolysis Propep Physical damage 
ProteomicsCALCIUM-DEPENDENT PROTEOLYSIS OF THE ARABIDOPSIS DAMP PRECURSOR PROPEP1 BY THE CYSTEINE PROTEASE METACASPASE4 REVEALS A CONSERVED MECHANISM FOR IMMEDIATE RELEASE OF PEPTIDE SIGNALS DURING WOUND RESPONSES
In animals, one of the most immediate responses to tissue wounding comprises the release of peptide signals such as interleukins from their precursor proteins. Although the wound response has been intensively studied in plants as well, little is known about plant peptides with cytokine-like function...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-23 | PXD005740 | Pride
Peptidomics Propep1 Metacaspase Arabidopsis 
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