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MetabolomicsDual metal electrolysis in theta capillary for lipid analysis

Increasing studies associating glycerophospholipids with various pathological conditions highlight the need for their thorough characterization. However, the intricate composition of the lipidome due to the presence of lipid isomers poses significant challenges to structural lipidomics. This stud...

2023-10-10 | MTBLS8547 | MetaboLights
ProteomicsMass spectrometry data supporting "Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates demetalation with pathology"
Protein-metal complexes implicated in the pathogenesis of amyotrophic lateral sclerosis were mapped by mass spectrometry imaging. Metal-deficient hSOD1G93A complexes were revealed to be localised with disease pathology in the spinal cord and brain.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-15 | PXD053247 | Pride
Protein-metal complexes Als Nano-desi Native ms Imaging 
TranscriptomicsMycobacterial cells have dual nickel-cobalt sensors: sequence-relationships and metal-sites of metal-responsive repressors are not congruent.
A novel ArsR-SmtB family transcriptional repressor, KmtR, has been characterised from mycobacteria. Mutants of M. tuberculosis lacking kmtR show elevated expression of Rv2025c encoding a deduced CDF-family metal-exporter. KmtR-dependent repression of the cdf and kmtR operator-promoters was alleviate...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-17 | E-BUGS-49 | biostudies-arrayexpress
ProteomicsStructurally related hydrazone-based metal complexes with different antitumor activities variably induce apoptotic cell death
Three new complexes bearing the tridentate hydrazone-based ligand 2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)pyridine (L) were synthesized and structurally characterized. Biological tests indicate that the Zn(II) complex [ZnCl2(L)] • 0.5 H2O is of low cytotoxicity against the hepatocellular carcino...
ORGANISM(S): Homo sapiens (Human) 
2017-05-03 | PXD005507 | Pride
Lc-ms/ms Metal complexes Liver cancer 
UnknownCharge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes.
Not available
S-EPMC9736222 | biostudies-literature
UnknownStable Luminescent [Cu(NN)(PP)]+ Complexes Incorporating a β-Cyclodextrin-Based Diphosphane Ligand with Metal-Confining Properties.
Not available
S-EPMC10107221 | biostudies-literature
UnknownMetal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
Not available
S-EPMC9820345 | biostudies-literature
ProteomicsMembrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis
Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a previously unrecognized mechanism in Mycobacterium tuberculosis, the causative agent of tuberculosis, wh...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2025-12-15 | PXD070650 | Pride
Metal binding Tuberculosis Native ms 
UnknownIlluminating metal-ion sensors: benzimidazolesulfonamide metal complexes.
Not available
S-EPMC2975806 | biostudies-literature
UnknownMetal Complexes for Therapeutic Applications.
Not available
S-EPMC9374106 | biostudies-literature
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