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Mitotic chromosomes are among the most recognizable structures in the cell, yet for over a century their internal organization remains largely unsolved. We applied chromosome conformation capture methods, 5C and Hi-C, across the cell cycle and revealed two alternative three-dimensional folding state...
ORGANISM(S): Homo sapiens 
Metaphase-Chromosome-Organization
Conformation of the budding yeast pericentromere in metaphase
macroH2A1 ChIP-seq in G1/S phase and metaphase
Decreasing oocyte competence with maternal aging is a major factor in human infertility. To investigate the age-dependent molecular changes in a mouse model, we compared the expression profiles of metaphase II oocytes collected from 5-6 week old mice with those collected from 40-42 week old mice usi...
ORGANISM(S): Mus musculus 
Differential nucleosome organization in human interphase and metaphase chromosomes [MNase-Seq]
Differential nucleosome organization in human interphase and metaphase chromosomes [Mnase-seq]
Study question: Does storage time impact on transcriptome of slowly frozen cryopreserved human metaphase II (MII) oocytes? Summary answer: For the first time, we demonstrate that the length of cryostorage has no effect on the gene expression profile of human metaphase II oocytes. What is known alrea...
ORGANISM(S): Homo sapiens 
Genome-wide binding of the meiosis specific Rec8 cohesin subunit in metaphase I
Differential nucleosome organization in human interphase and metaphase chromosomes [ChemMap]
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