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MetabolomicsProcess-integrated engineered resting cells for biocatalytic production of rare natural sugars from sole methanol molecules
The biocatalytic conversion of green methanol, a promising feedstock, into high value-added products is seen as an attractive way to establish sustainable biomanufacturing. Although natural and engineered microorganisms can utilize methanol, efficiently converting C1 carbon into valuable chemicals r...
2026-06-22 | MTBLS14812 | MetaboLights
TranscriptomicsC1 metabolism in Corynebacterium glutamicum: an endogenous pathway for oxidation of methanol to carbon dioxide
Methanol is considered as an interesting carbon source in biobased microbial production processes. As Corynebacterium glutamicum is an important host in industrial biotechnology, in particular for amino acid production, we performed studies on the response of this organism to methanol. C. glutamicum...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-09-27 | E-GEOD-49936 | biostudies-arrayexpress
TranscriptomicsPichia angusta cells glucose- vs methanol-grown
Transcriptional profiling of Pichia angusta NCYC 495 leu1.1 cells growing exponentially on mineral medium containing 0.5% glucose versus a shift for 2 hours to mineral medium containing 0.5% methanol. Two-conditions experiment, 4 individual glucose-grown cultures were shifted at OD660nm 2.3 to fresh...
ORGANISM(S): Pichia angusta NCYC 495 leu1.1 
2010-06-19 | E-GEOD-19036 | biostudies-arrayexpress
TranscriptomicsGene expression of M. acetivorans producing ANME-1 Mcr during growth on methane vs. growth on methanol
Our goal is to convert methane efficiently into liquid fuels that may be more readily transported. Since aerobic oxidation of methane is less efficient, we focused on anaerobic processes to capture methane, which are accomplished by anaerobic methanotrophic archaea (ANME) in consortia. However, no p...
ORGANISM(S): Methanosarcina acetivorans 
2015-12-20 | E-GEOD-66445 | biostudies-arrayexpress
TranscriptomicsEngineered Methylobacterium methanol
Engineered Methylobacterium methanol batch exponential strain CM702 vs. strain CM502
ORGANISM(S): Methylobacterium extorquens AM1 
2014-12-22 | E-GEOD-34662 | biostudies-arrayexpress
TranscriptomicsMethanol effect on an E. coli BW25113 strain expressing heterologous mdh and das enzymes during or after growth on xylose
In this project we used the strain E. coli BW25113 ΔfrmA::frt (Δ(araD-araB)567, ΔlacZ4787(::rrnB-3), λ-, rph-1, Δ(rhaD-rhaB)568, hsdR514, ΔfrmA(::frt)) from the Keio collection (Baba et al. 2006). The plasmid {pSEVA424_mdh-das} (Low-copy-number, lacIq/Ptrc promoter, RK2 ori, SmR) from Silva-Rocha et...
ORGANISM(S): Escherichia coli K-12 
2020-07-10 | E-MTAB-8909 | biostudies-arrayexpress
TranscriptomicsMouse brain tissue after methanol and normal saline treatment
We recently showed that methanol emitted by wounded plants might function as a signaling molecule for plant-to-plant and plant-to-animal communications. In mammals, methanol is considered a poison because the enzyme alcohol dehydrogenase (ADH) converts methanol into toxic formaldehyde. However, th...
ORGANISM(S): Mus musculus 
2014-06-10 | E-GEOD-58303 | biostudies-arrayexpress
ProteomicsComparative proteomics of Desulfotomaculum kuznetsovii grown on methanol and ethanol
The aim of this study was to unravel the methanol metabolism of Desulfotomaculum kuznetsovii. Anaerobic methylotrophs, such as methanogens and acetogens, use a pathway initiated by a cobalamine-containing methanol methyltransferase, whereas aerobic methylotrophs generally oxidize methanol to formald...
ORGANISM(S): Desulfotomaculum kuznetsovii DSM 6115 
2018-01-22 | PXD006899 | Pride
Metabolism Ethanol Methanol Lactate Sulfate reducing bacteria 
TranscriptomicsRNA-seq analysis of methanol-adapted Sporomusa ovata DSM-2662
Expression profile of wild-type S. ovata and methanol-adapted strain grown autotrophically with H2 as the source of electron. Illumina RNA-Seq of total RNA extracted from a strain of S. ovata evolved by adaptive laboratory evolution to grow faster with methanol 2% as the sole susbtrate and from the ...
ORGANISM(S): Sporomusa ovata DSM 2662 
2016-02-22 | E-GEOD-66194 | biostudies-arrayexpress
TranscriptomicsPichia pastoris Glucose/Methanol comparison
Comparison of transcription profile of Pichia pastoris cells grown on Glucose medium with Pichia pastoris cells grown on Methanol/Glycerol medium, the fermentations were done in a chemostat. 2 color experiment in reference design. Pichia pastoris reference mix [mixed pool of Pichia pastoris cells sa...
ORGANISM(S): Komagataella pastoris CBS 7435 
2015-08-31 | E-GEOD-67690 | biostudies-arrayexpress
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