Methyl transfer

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Transcriptomics (1998)
Unknown (1650)
Genomics (308)
Metabolomics (210)
Proteomics (105)
Other (2)
Models (1)
Genomic (1)
Methylation profiling (1)
Multiomics (1)

Organisms

Homo sapiens (439)
Mus musculus (417)
Drosophila melanogaster (181)
Caenorhabditis elegans (169)
Rattus norvegicus (135)
Saccharomyces cerevisiae (118)
Arabidopsis thaliana (116)
Schizosaccharomyces pombe (67)
Chlamydomonas reinhardtii (33)
Candida albicans (18)
Danio rerio (14)
Oryza sativa (13)
Mycobacterium tuberculosis (13)
Bos taurus (13)
Streptomyces venezuelae (12)
Escherichia coli (12)
Folsomia candida (10)
Dictyostelium discoideum (10)
Sus scrofa (9)
Escherichia coli K-12 (9)
Zea mays (8)
Solanum tuberosum (8)
Oryza sativa Japonica Group (8)
Agrobacterium tumefaciens (7)
Rhizobium leguminosarum (7)
Bacillus amyloliquefaciens (7)
Trypanosoma brucei (7)
Hordeum vulgare (7)
Oncorhynchus mykiss (7)
Sinorhizobium meliloti (7)

Organisms

Mus musculus (7)
Homo sapiens (5)
Adineta vaga (3)
Populus tremuloides (2)
Escherichia coli (2)
Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 (1)
subsurface metagenome (1)
Bos taurus (1)

Repository

biostudies-arrayexpress (2273)
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pride (63)
ENA (32)
MassIVE (25)
geo (15)
EGA (11)
iProX (5)
jPOST (5)
BioModels (1)
dbGaP (1)
GNPS (1)

Tissue

Cell culture (12)
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Root (2)
Urine (2)
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Blood (1)
Blood plasma (1)
Blood serum (1)
Culture condition:CD4+ cell (1)
Culture fluid (1)
Embryo (1)
Epithelial cell (1)
Erythrocyte (1)
Flower bud (1)
Heart (1)
Intestine (1)
Primary cell line cell (1)
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T cell (1)
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Disease

Normal (20)
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Alzheimer's disease (2)
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Blumeria graminis hordei (powdery mildew) inoculation (1)
Cutaneous melanoma (1)
Hypertension (1)
Imatinib-resistant CML cell line subclone (1)
Squamous cell carcinoma has accession C0007137 in DiseaseStateDatabase NCI_Thesaurus (1)
Infected with Influenza A/WSN/33 (H1N1) (1)
Photoreceptor degeneration (1)
Infiltrating ductal carcinoma (1)
Chronic granulomatous disease (1)
Primary tumor (1)
Oligodendroglioma (1)
Malignant fibrous histiocytoma (1)
Giant cell glioblastoma (1)
IRAK-4 Q293X mutation (1)
Infected (1)

Technology Type

Mass spectrometry (146)
Mass Spectrometry (63)
Mass spectrometry assay (54)
Shotgun proteomics (33)
Affinity purification coupled with mass spectrometry proteomics (10)
Bottom-up proteomics (10)
NMR spectroscopy (7)
Data-dependent acquisition (7)
Gel-based experiment (5)
Top-down proteomics (5)
NMR spectroscopy assay (3)
Data-independent acquisition (3)
Affinity proteomics (2)
Proteogenomics (2)
Illumina HiSeq 2000 (1)
All-ion fragmentation (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
DiaPASEF (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2000 (40)
Illumina NovaSeq 6000 (30)
BGISEQ-500 (22)
NextSeq 500 (22)
Illumina HiSeq 2500 (18)
Illumina HiSeq 4000 (18)
Axon GenePix 4000B scanning hardware (14)
Scanning hardware (7)
DNBSEQ-T7 (7)
Illumina Genome Analyzer IIx (6)
GenePix 4000B [Axon Instruments] (6)
ScanArray 5000 [PerkinElmer] (5)
G2565AA DNA microarray scanner [Agilent] (5)
Illumina Genome Analyzer II (5)
Illumina MiSeq (5)
GenePix 4000A [Axon Instruments] (4)
Axon- GenePix4000B (4)
ArrayWoRx Biochip Reader [Applied Precision] (3)
Other (3)
ScanArray Express HT [PerkinElmer] (3)
NextSeq 2000 (3)
NextSeq 550 (3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
FS450 (2)
GCS3000 (2)
Nanodrop N1000 spectrophotometer (2)
Ultracentrifuge (2)
ScanArray 4000 [PerkinElmer] (2)
Agilent G2565BA (2)
AB SOLiD 4 System (2)

Publication Date

2013 (383)
2010 (322)
2014 (209)
2011 (196)
2012 (184)
2015 (183)
2008 (129)
2009 (121)
2016 (112)
2026 (98)
2007 (83)
2025 (69)
2024 (56)
2022 (56)
2023 (53)
2006 (53)
2017 (51)
2021 (50)
2005 (42)
2020 (40)
2004 (36)
2018 (31)
2019 (29)
2003 (4)
2027 (1)

CHEBI ID

CHEBI:30769 (61)
CHEBI:15428 (60)
CHEBI:15741 (60)
CHEBI:18012 (51)
CHEBI:15756 (50)
CHEBI:28044 (45)
CHEBI:28842 (44)
CHEBI:27266 (43)
CHEBI:17992 (41)
CHEBI:25017 (41)
CHEBI:30915 (41)
CHEBI:6650 (40)
CHEBI:17822 (39)
CHEBI:18237 (39)
CHEBI:18186 (39)
CHEBI:17268 (38)
CHEBI:16449 (38)
CHEBI:22660 (37)
CHEBI:16000 (37)
CHEBI:17568 (37)
CHEBI:26271 (36)
CHEBI:24898 (36)
CHEBI:16865 (36)
CHEBI:16704 (36)
CHEBI:18257 (35)
CHEBI:17754 (35)
CHEBI:16958 (35)
CHEBI:32816 (35)
CHEBI:17234 (34)
CHEBI:30746 (34)

Metabolite Name

Glycine (35)
Citric acid (34)
Sucrose (33)
Succinic acid (31)
Uridine (30)
Fumaric acid (29)
Taurine (28)
Malic acid (27)
Inosine (27)
Pyroglutamic acid (26)
Benzoic acid (26)
Uracil (25)
Adenine (25)
L-Tyrosine (25)
L-Phenylalanine (25)
Glycerol (24)
Ornithine (24)
L-Asparagine (24)
L-Threonine (24)
Alanine (24)
Palmitic acid (24)
Leucine (23)
Succinic acid (23)
L-Lysine (23)
L-Proline (23)
Stearic acid (23)
Phenylalanine (23)
Guanosine (23)
Hypoxanthine (23)
Glycolic acid (22)

First Public Date

2025 (6)
2026 (5)
2022 (5)
2014 (4)
2024 (2)
2019 (2)
2018 (2)
2017 (2)
2023 (1)
2021 (1)
2020 (1)
2016 (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Department of Parasitology, Faculty of Science, Charles University, BIOCEV, Průmyslová 595, 25242 Vestec, Czech Republic (2)
Department of Zoology, Faculty of Science, Charles University, BIOCEV, Vestec and Prague, Czech Republic (2)
A.N. Bach Institute of Biochemistry, Federal Research Centre ‘Fundamentals of Biotechnology’ of the Russian Academy of Sciences, Leninsky pr., 33, 119071, Moscow, Russia (1)
Advanced Research Centre (ARC) College of Medical, Veterinary and Life Sciences University of Glasgow, Glasgow, UK. (1)
Agrochemistry and Biochemistry Department. University of Alicante (1)
Associate Professor, Department of Microbiology and Immunology (1)
BIOCEV group, Department of Zoology, Faculty of Science, Charles University in Prague, Průmyslová 595, 252 42 Vestec (1)
Beth Israel Deaconess Medical Center and Harvard Medical School (1)
Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA (1)
Biomedical Research Centre, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic (1)
Biomolecular Mass Spectrometry and Proteomics (1)
Cellular Proteomics Group Helmholtz Centre for Infection Research Inhoffenstr. 7 38124 Braunschweig Germany (1)
Chemical and Biological engineering, The University of Sheffield (1)
Department of Applied Biological Science, College of Bioresource Sciences, Nihon University (1)
Department of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute (FABI),Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa (1)
Department of Biological Sciences, Vanderbilt University (1)
Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, 7535, South Africa (1)
Department of Chemistry and Bioscience, Aalborg University, Denmark (1)
Department of Chemistry, Univeristy of North Carolina at Chapel Hill (1)
Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 75123, Uppsala, Sweden (1)
Department of Parasitology, Faculty of Science, Charles University, BIOCEV, Průmyslová 595, 252 50, Vestec, Czech Republic (1)
Department of Zoology, Faculty of Science, Charles University in Prague (1)
Department of Zoology, Faculty of Science, Charles University, Czech Republic (1)
Departments of Neuroscience and Psychiatry, The Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. (1)
Division of Infection Medicine, Department of Clinical Sciences, Lund, Lund University, Biomedical Center, Tornavägen 10, SE-22184 Lund, Sweden (1)
Faculty of Chemistry, Chair of Drug and Cosmetics Biotechnology, Warsaw University of Technology, Warsaw, Poland (1)
Faculty of Forestry and Wood Sciences, Czech University of Life Sciences Prague, Czech Republic. (1)
Genome Center of Wisconsin,Department of Chemistry, Department of Biomolecular Chemistry, and DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI 53706, USA Morgridge Institute for Research, Madison, WI 53706, USA (1)
Glycoproteomics Laboratory, Institute of Biomedical Sciences, University of São Paulo (1)
Gregor Mendel Institute of Molecular Plant Biology (GMI), Dolan lab, Dr. Bohr-Gasse 3, 1030 Vienna, Austria (1)

IsPrivate

False (1)

Classification

bacteria (2)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (1239)
RNA-seq of coding RNA (269)
ChIP-seq (230)
ChIP-chip by tiling array (130)
RNA-seq of non coding RNA (63)
Other (46)
ChIP-chip by array (45)
Unknown experiment type (40)
Comparative genomic hybridization by array (39)
DNA-seq (22)
Methylation profiling by array (22)
RNA-seq of coding RNA from single cells (14)
Methylation profiling by high throughput sequencing (10)
Transcription profiling by tiling array (9)
High-throughput sequencing (8)
RIP-seq (8)
Proteomic profiling by array (8)
Cell line - High-throughput sequencing (6)
RNAi profiling by array (6)
MicroRNA profiling by array (5)
RNA-seq of total RNA (5)
Genotyping by array (4)
CLIP-seq (4)
Transcription profiling by RT-PCR (3)
Spatial transcriptomics by high-throughput sequencing (3)
Cell line - One-color microarray (2)
Translation profiling (2)
Transcription profiling by array, ChIP-chip by array (1)
GRO-seq (1)
Transcription profiling by SAGE (1)

Release Date

2013 (431)
2010 (365)
2014 (255)
2015 (244)
2012 (234)
2011 (233)
2022 (186)
2016 (175)
2025 (170)
2023 (170)
2008 (156)
2009 (154)
2024 (148)
2020 (146)
2021 (143)
2019 (137)
2017 (120)
2018 (99)
2007 (99)
2006 (75)
2026 (58)
2005 (54)
2004 (41)
2003 (9)
2002 (8)
2001 (6)
1999 (3)
2000 (2)
1998 (1)
1997 (1)

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LC-MS untargeted approach showed that methyl jasmonate application on Vitis labrusca L. grapes increases phenolics at subtropical Brazilian regions

Vitis labrusca L. grapes are largely cultivated in Brazil, but the tropical climate affect negatively the phenols content, especially anthocyanin. Therefore, researches are focusing on increase grape phenols content; with methyl jasmonate application (MeJa) considered a good alternative.

T...

2020-05-26 | MTBLS784 | MetaboLights

Co-occurrence of direct and indirect extracellular electron transfer mechanisms during electroactive respiration in a dissimilatory sulfate reducing bacterium

Understanding the extracellular electron transfer mechanisms of electroactive bacteria could help determine their potential in microbial fuel cells (MFCs) and their microbial syntrophy with redox-active minerals in natural environments. However, the mechanisms of extracellular electron transfer t...

2024-12-06 | MTBLS11447 | MetaboLights

Synergistic regulation of Codonopsis pilosula growth and metabolism by Trichoderma, salicylic acid and methyl jasmonate

Endophytic fungi can mediate salicylic acid (SA)- and methyl jasmonate (MeJA)-related signaling in medicinal plants, thereby influencing metabolite synthesis, stress resistance, and growth development. Experimental groups comprised control, Trichoderma longibrachiatum inoculation (FG), FG+SA (FS), F...

2026-04-16 | MTBLS14293 | MetaboLights

Synergistic regulation of Codonopsis pilosula growth and metabolism by Trichoderma, salicylic acid and methyl jasmonate

2026-04-22 | MTBLS14304 | MetaboLights

Metabolomics reveals increased toxicity in earthworms (Eisenia fetida) of the transformation product methyl-triclosan

The effects of the antimicrobial triclosan (TCS) and its transformation product methyl-triclosan (MTCS) on the earthworm Eisenia fetida were investigated using GC-MS metabolomics. TCS is ubiquitous in sewage sludge, but a large proportion is transformed into MTCS during wastewater treatment and in s...

2018-09-17 | MTBLS532 | MetaboLights

Investigation of Brazilian grape juice metabolomic profile changes caused by methyl jasmonate pre-harvest treatment

Grape juice is a major source of potential health-promoting bioactive polyphenols, especially for children and those who do not consume wine. Since the subtropical climate may negatively affect the concentrations of grape polyphenols, especially anthocyanins, elicitors such as methyl jasmonate (M...

2022-06-28 | MTBLS2401 | MetaboLights

LKB1 inactivation elicits a NNMT-mediated methyl sink and confers dependence on PRMT5 in lung cancer

The protein arginine methyl transferase 5 (PRMT5) emerges as a therapeutic target in S-methyl-5'-thioadenosine phosphorylase (MTAP)-deleted cancers, where MTA accumulation partially inhibits its activity. However, It remains unclear whether other genetic alterations can dictate PRMT5 activity in can...

2026-04-30 | MTBLS14411 | MetaboLights

Mechanisms of Iprovalicarb and Cycluron in Promoting Conjugative Transfer of Antibiotic Resistance Genes and Outer Membrane Vesicle-Mediated Dissemination

Detect pesticide residues in water, manure, and soil from waterfowl farms.

2026-08-07 | MTBLS15288 | MetaboLights

Chromatin immunoprecipitation of transcription factor binding in yeast cells perturbed with methyl-methanesulfonate

Genome-wide promoter-binding analysis of transcription factors in S.cerevisiae cells perturbed with 0.03% methyl-methanesulfonate for 60 minutes

ORGANISM(S): Saccharomyces cerevisiae

2006-05-19 | E-TABM-92 | biostudies-arrayexpress

Transcription profiling of yeast transcription factor deletion strains perturbed with methyl-methanesulfonate

Gene expression profiles of transcription factor deletion strains (S.cerevisiae) perturbed with 0.03% methyl-methanesulfonate for 60 minutes

ORGANISM(S): Saccharomyces cerevisiae

2006-05-19 | E-TABM-93 | biostudies-arrayexpress