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FICC-Seq: A method for enzyme-specified profiling of methyl-5-uridine in cellular RNA
Methyl-5-uridine (m5U) is one the most abundant non-canonical bases present in cellular RNAs, and is formed via catalytic conversion of uridines. In yeast, m5U is known to be present at position 54 of tRNAs where modification is catalysed by the methyltransferase Trm2. Although the mammalian enzymes...
ORGANISM(S): Homo sapiens 
2019-07-03 | GSE109183 | GEO
Methyl-5-uridine (m5U) is one of the most abundant RNA modifications found in cytosolic tRNA. tRNA methyltransferase 2 homolog A (hTRMT2A) is the dedicated mammalian enzyme of m5U conversion at tRNA position 54. However, its RNA binding specificity and functional role in the cell are not well unders...
ORGANISM(S): Homo sapiens (Human) 
2023-07-04 | PXD036538 | Pride
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