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MetabolomicsVisceral obesity-Induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression

The incidence of obesity and colorectal cancer (CRC) is rising annually. Obesity, particularly visceral obesity, poses a serious health threat, yet the association of obesity with CRC progression, as well as the role of visceral obesity, remains debated. This study analyzed 394 CRC patients ...

2025-10-06 | MTBLS13095 | MetaboLights
ProteomicsIdentification of METTL5 interaction partners
METTL5 is an RNA methyltransferase whose stability was noted to be poor when expressed in both mammalian and bacterial expression systems. To determine if METTL5 has an endogenous stabilizing binding partner, FLAG-tagged METTL5 was expressed in Freestyle 293 cells and pulled down with anti-FLAG-M2 a...
ORGANISM(S): Homo sapiens (Human) 
2022-01-27 | PXD029574 | Pride
Mettl5 
GenomicsIdentifying METTL5-bound RNA by crosslinking-assisted immunoprecipitation
Identifying METTL5-bound RNA by crosslinking-assisted immunoprecipitation
PRJNA729821 | ENA
GenomicsResolving METTL5 Specificity: Direct RNA Sequencing Reveals No Evidence for METTL5 mediated mRNA m6A Methylation in mESCs
Resolving METTL5 Specificity: Direct RNA Sequencing Reveals No Evidence for METTL5 mediated mRNA m6A Methylation in mESCs
PRJNA1454497 | ENA
GenomicsMapping translation in wild-type and METTL5 knockout (KO) mice
Mapping translation in wild-type and METTL5 knockout (KO) mice
PRJNA780403 | ENA
GenomicsFunction and Mechanism of METTL5-mediated translation in multiple myeloma
Function and Mechanism of METTL5-mediated translation in multiple myeloma
PRJNA1250600 | ENA
UnknownMETTL5 regulates cranial suture fusion via Wnt signaling.
Not available
S-EPMC11197682 | biostudies-literature
GenomicsMapping translation in wild-type and METTL5 knockout (KO) HepG2 cells
Mapping translation in wild-type and METTL5 knockout (KO) HepG2 cells
PRJNA729866 | ENA
GenomicsMETTL5 deficiency induces lung cancer regression via mitochondrial translation reduction
METTL5 deficiency induces lung cancer regression via mitochondrial translation reduction
PRJNA1136550 | ENA
UnknownScutellarin suppresses ovarian cancer progression by targeting METTL5.
Not available
S-EPMC12117153 | biostudies-literature
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