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TranscriptomicsTranscription profiling of human chronic lymphocytic leukemia cells treated with valproic acid
Epigenetic code modifications by histone deacetylase inhibitors (HDACi) have recently been proposed as potential new therapies for hematological malignancies. Chronic Lymphocytic Leukemia (CLL) remains incurable despite the introduction of new treatments. CLL cells are characterized by an apoptosis ...
ORGANISM(S): Homo sapiens 
2009-09-17 | E-GEOD-14973 | biostudies-arrayexpress
UnknownDevelopment and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1.
Not available
S-EPMC5784761 | biostudies-literature
UnknownLenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma.
Not available
S-EPMC6201242 | biostudies-literature
TranscriptomicsEvolutionary conservation of nuclear lamina-genome interactions
Regulation of gene expression is highly conserved between vertebrates, yet the genomic binding patterns of transcription factors are poorly conserved, suggesting that other mechanisms may contribute. The spatial organization of chromosomes in the nucleus is known to affect gene activity, but it is u...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-22428 | biostudies-arrayexpress
UnknownGenome-wide haplotyping embryos developing from 0PN and 1PN zygotes increases transferrable embryos in PGT-M.
Not available
S-EPMC6238370 | biostudies-literature
TranscriptomicsEpigenetic profiles of CRC-derived samples by scGET-seq
Multiple samples of Patient Derived Xenografts (PDX) of a EGFR-resistant colorectal cancer are recovered at different times and profiled by scGET-seq.
ORGANISM(S): Homo sapiens 
2021-08-17 | E-MTAB-9659 | biostudies-arrayexpress
UnknownGlobal histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patients.
Not available
S-EPMC4622440 | biostudies-literature
UnknownData on nitric oxide production by human bone marrow-derived mesenchymal stromal cells.
Not available
S-EPMC4976668 | biostudies-literature
UnknownCharacterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance.
Not available
S-EPMC5141649 | biostudies-literature
TranscriptomicsThe insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome: expression
Specific interactions of the genome with the nuclear lamina (NL) are thought to assist chromosome folding inside the nucleus and to contribute to the regulation of gene expression. High-resolution mapping has recently identified hundreds of large, sharply defined lamina-associated domains (LADs) in ...
ORGANISM(S): Drosophila melanogaster 
2011-01-24 | E-GEOD-20312 | biostudies-arrayexpress
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