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MetabolomicsUntargeted metabolomics links glutathione to bacterial cell cycle progression
Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargete...
2020-10-15 | MTBLS1402 | MetaboLights
TranscriptomicsATAC-seq of Mus musculus embryonic cell types in response to Pbx1 knockout
ATAC-seq was performed, mapped, and analyzed as previously described (PMID: 34446717: \\"ATAC-seq was performed on 50,000 cells per replicate as described in Buenrostro et al. (with modifications based on Corces et al.), on EpiSCs and PSM-differentiated cell populations at desired time-points. Libra...
ORGANISM(S): Mus musculus 
2023-12-01 | E-MTAB-13407 | biostudies-arrayexpress
MetabolomicsUntargeted extraction of metabolites 13C labeling profiles from time course labeling switch experiment
Dynamic isotope labeling data provide crucial information about the operation of metabolic pathways, and are commonly generated via liquid chromatography mass spectrometry (LC-MS). Metabolome-wide analysis is challenging as it requires grouping of metabolite features over different samples. We devel...
2015-10-19 | MTBLS228 | MetaboLights
MetabolomicsUntargeted extraction of metabolites 13C labeling profiles from time course labeling switch experiment
Dynamic isotope labeling data provide crucial information about the operation of metabolic pathways, and are commonly generated via liquid chromatography mass spectrometry (LC-MS). Metabolome-wide analysis is challenging as it requires grouping of metabolite features over different samples. We devel...
2015-10-19 | MTBLS229 | MetaboLights
UnknownSmad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma.
Not available
S-EPMC10618913 | biostudies-literature
UnknownInternational practices in the dietary management of fructose 1-6 biphosphatase deficiency.
Not available
S-EPMC5785792 | biostudies-literature
ProteomicsTherapeutic targeting of ATR in alveolar rhabdomyosarcoma
Despite advances in multi-modal treatment approaches, clinical outcomes of patients suffering from PAX3-FOXO1 fusion oncogene-expressing alveolar rhabdomyosarcoma (ARMS) remain dismal. Here we show that PAX3-FOXO1-expressing ARMS cells are sensitive to pharmacological ataxia telangiectasia and Rad3 ...
ORGANISM(S): Homo Sapiens (human) 
2022-07-11 | PXD035131 | JPOST Repository
ModelsMorpheus: open source modelling and simulation framework for multicellular systems
Morpheus: open source modelling and simulation framework for multicellular systems
2018-06-08 | 320 | FAIRDOMHub
UnknownThe development of a HAMstring InjuRy (HAMIR) index to mitigate injury risk through innovative imaging, biomechanics, and data analytics: protocol for an observational cohort study.
Not available
S-EPMC9288010 | biostudies-literature
UnknownHeterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).
Not available
S-EPMC11586762 | biostudies-literature
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