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TranscriptomicsSingle cell derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
Single cell derived clones were extracted from four glioblastoma tumors using fluorescence activated cell sorting with CD15 and CD133 markers. Unsorted bulk tumors were also derived. Gene expression analysis of clones of tumor GBM-482 involved comparison between TMZ resistant (n=5) and sensitive (n=...
ORGANISM(S): Homo sapiens 
2015-01-03 | E-MTAB-2693 | biostudies-arrayexpress
TranscriptomicsSingle cell derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
Single cell derived clones were extracted from four glioblastoma tumors using fluorescence activated cell sorting with CD15 and CD133 markers. Unsorted bulk tumors were also derived. Genotyping and copy number analysis was carried out for each tumor separately. Patient blood was used as control for ...
ORGANISM(S): Homo sapiens 
2015-01-03 | E-MTAB-2694 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of J774A.1 macrophages undergoing amino acid deprivation
Phagocytosis represents a mechanism used by macrophages to remove pathogens and cellular debris. Recent evidence suggested that amino acid or glucose deprivation may cause an increase in phagocytosis of heat-inactivated Escherichia coli and Staphylococcus aureus by macrophages, but not the uptake of...
ORGANISM(S): Mus musculus 
2010-05-06 | E-GEOD-14293 | biostudies-arrayexpress
UnknownRadiation Dosimetry and Biodistribution of 68Ga-FAPI-46 PET Imaging in Cancer Patients.
Not available
S-EPMC7413240 | biostudies-literature
UnknownTargeted alpha therapy in a systemic mouse model of prostate cancer - a feasibility study.
Not available
S-EPMC7052903 | biostudies-literature
TranscriptomicsTranscriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii
Two S. rolfsii transcriptomes obtained from scleroglucan-producing and scleroglucan-nonproducing conditions were pooled and sequenced using the 454 pyrosequencing technique yielding ~350,000 reads. These could be assembled into 21,937 contigs and 171,833 singletons, for which 6,951 had significant m...
ORGANISM(S): Athelia rolfsii 
2010-05-15 | E-GEOD-21040 | biostudies-arrayexpress
MetabolomicsUncovering the secrets of monoculture yield decline: Trade-offs between leaf and root chemical and physical defence traits in a grasslands experiment

Plant monocultures growing for extended periods face severe losses of productivity. This phenomenon, known as 'yield decline', is often caused by the accumulation of above- and below-ground plant antagonists. The effectiveness of plant defences against antagonists might help explain differences i...

2023-11-03 | MTBLS4286 | MetaboLights
TranscriptomicsProspective derivation of a 'Living Organoid Biobank' of colorectal cancer patients
In Rspondin-based three-dimensional cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. Here we report the establishment of tumor organoid cultures from 20 consecutive colorectal carcinoma (CRC) patients. For most, organoids were...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-65253 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis wild type and PII deficient plants grown on different nitrogen sources
In E.Coli, PII protein is known to be a sensor of medium nitrogen status and to regulate some nitrogen metabolism steps (e.g.glutamin synthase and ammonium transporter regulations). Arabidopsis PII protein is the only homolog gene found in the arabidopsis genome and its role is still unclear. The go...
ORGANISM(S): Arabidopsis thaliana 
2007-01-13 | E-MEXP-446 | biostudies-arrayexpress
TranscriptomicsHelicobacter pylori induce miR-155 in T cells in a cAMP-Foxp3 dependant manner
The human pathogen Helicobacter pylori (Hp) colonizes the gastric epithelium as a unique niche in the stomach. Infections commonly occur in childhood and persist lifelong, leading in some cases to adenocarcinoma and MALT lymphoma. Several studies define mammalian microRNAs as key regulators of the i...
ORGANISM(S): Mus musculus 
2010-12-22 | E-GEOD-18616 | biostudies-arrayexpress
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