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TranscriptomicsMyocardial infarction time series single cell RNA-Seq
The outcome of cardiac repair post myocardial infarction is highly dependent on the balance between inflammation and fibrosis, which can lead to adverse ventricular remodeling and failure or early cardiac rupture. In order to profile the dynamic response of the interstitium to cardiac ischemic injur...
ORGANISM(S): Mus musculus 
2020-03-04 | E-MTAB-7895 | biostudies-arrayexpress
UnknownPDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
Not available
S-EPMC5738926 | biostudies-literature
MetabolomicsMRG15 orchestrates glycolysis and the pentose phosphate pathway to facilitate heart regeneration following myocardial infarction
Metabolic reprogramming is crucial for adult heart regeneration after myocardial infarction (MI). Here, we identify the MORF4-related gene on chromosome 15 (MRG15) as a key orchestrator of cardiomyocyte metabolism to drive cardiomyocyte proliferation. MRG15 expression is upregulated in both hypoxic ...
2026-09-22 | MTBLS15769 | MetaboLights
MetabolomicsMRG15 orchestrates glycolysis and the pentose phosphate pathway to facilitate heart regeneration following myocardial infarction
Metabolic reprogramming is crucial for adult heart regeneration after myocardial infarction (MI). Here, we identify the MORF4-related gene on chromosome 15 (MRG15) as a key orchestrator of cardiomyocyte metabolism to drive cardiomyocyte proliferation. MRG15 expression is upregulated in both hypoxic ...
2026-09-22 | MTBLS15770 | MetaboLights
GenomicsMITF ChIP-seq in primary melanocyte and melanoma as a function of oncogenic BRAF
Thousands of enhancers are characterized in the human genome, yet few have been shown important in cancer. Inhibiting oncokinases, such as EGFR, ALK, HER2, and BRAF, is a mainstay of current cancer therapy but is hindered by innate drug resistance mediated by upregulation of the HGF receptor, MET. T...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-50681 | biostudies-arrayexpress
TranscriptomicsThe human airway epithelial basal cell transcriptome in the early response to injury
Background: Basal cells within the human airway epithelium constitute the stem/progenitor cells for other epithelial cell types. Basal cells respond to mucosal injury and damage to the airway mucosa in an ordered sequence of spreading, migration, proliferation and phenotype shifting (differentiation...
ORGANISM(S): Homo sapiens 
2015-04-30 | E-GEOD-59128 | biostudies-arrayexpress
Proteomicsc-JUN interacte with NuRD complex to regulate chromatin remodeling
detect c-JUN interaction proteins in humanembryonic stem cells
ORGANISM(S): Homo Sapiens 
2023-12-28 | PXD048153 |
UnknownPrimary Mechanism Study of Panax notoginseng Flower (Herb) on Myocardial Infarction in Rats.
Not available
S-EPMC6525894 | biostudies-literature
TranscriptomicsTranscription profiling of mouse RARgamma responsive genes in F9 teratocarcinoma cells
We compared the differentially expressed genes between the F9 Wt cells and F9 RAR gamma knock out cells before and after RA treatment. 3 replicates for each conditions. We also identified the RA responsive genes in the F9 Wt cells. Experiment Overall Design: F9 wt cells and F9 RAR gamma knock out ce...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8431 | biostudies-arrayexpress
UnknownIdentification of hub biomarkers of myocardial infarction by single-cell sequencing, bioinformatics, and machine learning.
Not available
S-EPMC9357907 | biostudies-literature
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