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TranscriptomicsTranscription profiling of S. cerevisiae wild type versus delta vts1
The experiment was designed to look for genes up/downregulated in the absense of Vts1p compared to wild-type cells grown in steady state conditions. Experiment Overall Design: 3 chips delta VTS1 vs. 2 wild type control chips
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-12 | E-GEOD-3859 | biostudies-arrayexpress
TranscriptomicsTranscriptome analyses of ragged seedling2 shoot apical meristem (SAM) vs non-mutant SAM
The recessive mutation ragged seedling2-R (rgd2-R) conditions defective lateral development of maize leaves. Although dorsiventral patterning is established in rgd2-R mutant leaves, some swapping of adaxial/abaxial epidermal identity may occur. Molecular analyses indicate that RGD2 is required for...
ORGANISM(S): Zea mays 
2008-05-02 | E-GEOD-11325 | biostudies-arrayexpress
TranscriptomicsGene expression regulation by C. elegans SAM-10
Little is known about transcriptional control of neurite branching or presynaptic differentiation, events that occur relatively late in neuronal development. Using the C. elegans mechanosensory circuit as an in vivo model, we show that SAM-10, an ortholog of mammalian Single-Stranded DNA binding P...
ORGANISM(S): Caenorhabditis elegans 
2010-11-12 | E-GEOD-25285 | biostudies-arrayexpress
MetabolomicsSIN-3 transcriptional coregulator maintains mitochondrial homeostasis and polyamine flux
Mitochondrial function relies on the coordinated transcription of mitochondrial and nuclear genomes to assemble respiratory chain complexes. Across species, the SIN3 coregulator influences mitochondrial functions, but how its loss impacts mitochondrial homeostasis and metabolism in the context of a ...
2024-04-01 | MTBLS8439 | MetaboLights
GenomicsSimultaneous in vivo enzyme and host engineering through laboratory evolution
Two genetic selection systems that couple metabolite hydroxylation or methylation of small molecules to growth of Escherichia coli are presented in this study. One system targets pterin-dependent hydroxylation (tBPt) while another focuses on S-adenosylmethionine-dependent methylation (SAM). Using ad...
ORGANISM(S): Escherichia coli BW25113 
2019-01-30 | E-MTAB-6779 | biostudies-arrayexpress
MetabolomicsGNPS Mara1 Heterologous expression in S. albidoflavus J1074
Heterologous expression of Mara1 in S. ablidoflavus J1074. Mara1 is from S. mirabilis P8-A2
ORGANISM(S): Streptomyces Albidoflavus (ncbitaxon:1886) 
2024-01-26 | MSV000093927 | GNPS
UnknownBlasticidin S Biosynthesis Involves a Unique Interplay between a Radical SAM Dehydratase, a Transaminase and an ATP-Grasp Ligase in Order to Avoid a Futile Cycle.
Not available
S-EPMC12352542 | biostudies-literature
TranscriptomicsTranscriptomics of bryophyte apical cells and young sporophytes
Alternation of generations, in which the haploid and diploid stages of the life cycle are each represented by multicellular forms that differ in their morphology, is a defining feature of the land plants (embryophytes). Anciently derived lineages of embryophytes grow predominately in the haploid gam...
ORGANISM(S): Physcomitrella patens 
2014-10-30 | E-MTAB-4217 | biostudies-arrayexpress
TranscriptomicsEffects of PGRMC1 phosphorylation on genome integrity and epigenetics
Progesterone receptor membrane component 1 (PGRMC1) is a protein that has been implicated in cancer biology and poor patient outcomes, which can be over-expressed in cancers, and exist in alternative states of phosphorylation.Here, we show that manipulation of PGRMC1 phosphorylation by mutagenesis r...
ORGANISM(S): Homo sapiens 
2019-12-01 | E-MTAB-8218 | biostudies-arrayexpress
TranscriptomicsAI-2-dependent gene regulation in Staphylococcus epidermidis
Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling molecule, but in many bacteria AI-2 control of gene expression is not completely understood. ...
ORGANISM(S): Staphylococcus epidermidis 
2008-10-10 | E-GEOD-9427 | biostudies-arrayexpress
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