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GenomicsGenomic Study of RNA Polymerase II and III SNAPc-Bound Promoters Reveals a Gene Transcribed by both Enzymes and a Broad Use of Common Activators
SNAPc-dependent promoters are unique among cellular promoters in being very similar to each other, even though some of them recruit RNA polymerase II and other RNA polymerase III. We have examined all SNAPc-bound promoters present in the human genome. We find that there is a surprisingly small numbe...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-38303 | biostudies-arrayexpress
UnknownEndocranial volume increases across captive generations in the endangered Mexican wolf.
Not available
S-EPMC9114419 | biostudies-literature
TranscriptomicsTranscription profiling time series of a human conjunctival epithelial cell line treated with retinoic acid
Purpose. How vitamin A contributes to the maintenance of the wet-surfaced phenotype at the ocular surface is not well understood. We sought to identify vitamin A responsive genes in ocular surface epithelia using gene microarray analysis of cultures of a human conjunctival epithelial cell line (HCjE...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-2835 | biostudies-arrayexpress
UnknownAssociation between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors.
Not available
S-EPMC5004685 | biostudies-literature
TranscriptomicsTranscription profiling of field-caught permethrin-resistant Anopheles gambiae shows over-expression of CYP6P3, a P450 that metabolizes pyrethroids
Field-caught permethrin-resistant Anopheles gambiae s.s. overexpress CYP6P3, a P450 that metabolizes pyrethroids
ORGANISM(S): Anopheles gambiae s.s. 
2009-01-17 | E-MTAB-52 | biostudies-arrayexpress
UnknownGeneration of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity.
Not available
S-EPMC8340056 | biostudies-literature
ProteomicsTowards an upgraded honey bee (Apis mellifera L.) genome annotation using proteogenomics.
The honey bee is a key pollinator in many agricultural operations as well as a model organism for studying the genetics and evolution of social behaviour. The Apis mellifera genome has been sequenced and annotated twice over, enabling proteomics and functional genomics methods for probing relevant a...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Apis mellifera (Honeybee) Drosophila melanogaster (Fruit fly) Saccharomyces cerevisiae (Baker's yeast) Caenorhabditis elegans 
2016-01-18 | PXD002275 | Pride
Honey bees Proteogenomics Mass spectrometry Gene annotation Apis mellifera 
UnknownBrain region dependent molecular signatures and myelin repair following chronic demyelination.
Not available
S-EPMC10171432 | biostudies-literature
ProteomicsMultiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues
We developed 7,184 quantitative multiple reaction monitoring mass spectrometry (MRM-MS) assays that measure 2,118 unique proteins in 20 mouse organs and tissues to enable system-level analysis of protein expression in mice. Targets for assay development were selected by untargeted MS analysis, and c...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-03 | PXD021333 | Pride
Mouse tissue proteomics Proteomic phenotyping Mrm assay development Cptac Molecular phenotyping Stable isotope-labelled standards 
UnknownSTAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination.
Not available
S-EPMC7071888 | biostudies-literature
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