Sort   by:  
 Page size 
MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
TranscriptomicsTranscription profiling of mouse model for Werner syndrome
Werner syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS is believed to be involved in different aspects of transcription, replication, and/or DNA repair. The poly(ADP-ribose) polymerase-1 (PARP-1) enzyme is also in...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3359 | biostudies-arrayexpress
UnknownChromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.
Not available
S-EPMC7205870 | biostudies-literature
ProteomicsTEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest
Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...
ORGANISM(S): Homo Sapiens (human) 
2023-05-12 | PXD039726 | JPOST Repository
UnknownProspective Evaluation of Magnetic Resonance Imaging and [18F]Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography at Diagnosis and Before Maintenance Therapy in Symptomatic Patients With Multiple Myeloma Included in the IFM/DFCI 2009 Trial: Results of the IMAJEM Study.
Not available
S-EPMC5578392 | biostudies-literature
MetabolomicsCollected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research
MIADB: a cumulative collection of 172 tandem mass spectrometry (MS/MS) of a vast array of monoterpene indole alkaloids. Samples were analyzed using an Agilent LC-MS system composed of an Agilent 1260 Infinity HPLC coupled to an Agilent 6530 ESI-Q-TOF-MS operating in positive mode. A Sunfire analytic...
2018-12-03 | MTBLS142 | MetaboLights
TranscriptomicsCombined analysis of single cell RNA-Seq and ATAC-Seq data reveals regulatory toggles operating in native and iPS-derived retina
To improve the comparison of the developmental trajectories of native retina (NaR) and iPSC-derived 3D retinal aggregates(3D-RA) , we performed scRNA-Seq of murine NaR and 3D-RA at four matched stages of development: embryonic day (E)13 vs differentiation day (DD)13, postnatal day (P)0 vs DD21, P5 v...
ORGANISM(S): Mus musculus 
2021-06-30 | E-MTAB-9395 | biostudies-arrayexpress
OtherMolecular consequences of proprotein convertase 1/3 inhibition in macrophages for application to cancer immunotherapy: a proteomic study
Data from ProteomeXchange, PXD ID: PXD001984. File: KO_LPS1.mzml. Published as part of Mol Cell Proteomics. 2015 Sep 1 . From the Abstract: {{i}} ... Here, we investigated the intracellular impact of the down-regulation of the proprotein convertase 1/3 in NR8383 macrophages. A complete proteomic st...
ORGANISM(S): Mus_musculus_viruses, Rabbit_calicivirus_australia_1_mic_07_uid33267, Rattus_norvegicus_papillomavirus_1_ees_2009_uid40233, Rat_coronavirus_parker_uid39313, Rat 
GPM32310023533 | GPMDB
Resource Reanalysis 
TranscriptomicsATAC-Seq using native and iPSC-derived murine retina at three developmental stages.
To identify epigenetic programs underlying differentiation of mouse retina, we performed ATAC-Seq on bulk native retina (NaR) and iPSC-derived 3D retinal aggregates (3D-RA) at three matched stages of development: embryonic day (E)13 vs differentiation day (DD)13, postnatal day (P)0 vs DD21, and P5 v...
ORGANISM(S): Mus musculus 
2021-06-30 | E-MTAB-9440 | biostudies-arrayexpress
UnknownTRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
Not available
S-EPMC9338040 | biostudies-literature
Sort   by:  
 Page size