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MetabolomicsCore microbes are ecological generalists supporting the host and ecosystem functionality and stability
Core gut microbes persist across diverse gut ecosystems, raising the central question in microbiome research of what defines core microbes and the factors driving their persistence across hosts? Using the rumen microbiome as a model system, our study reveals that core microbes exhibit distinct attri...
2025-05-23 | MTBLS11446 | MetaboLights
MetabolomicsComparison of intestinal microbes and metabolites in active VKH versus acute anterior uveitis associated with ankylosing spondylitis

BACKGROUND: It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear.

METHODS:&...

2023-12-12 | MTBLS7936 | MetaboLights
MetabolomicsGlycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway configurations ...
2022-01-11 | MTBLS3887 | MetaboLights
MetabolomicsPhyllosphere microbes mediate variety-specific accumulation of di-n-butyl phthalate in choysum (Brassica parachinensis)

Plant-microbe interactions in the phyllosphere have been demonstrated to facilitate plant growth and enhance resistance to diverse stresses; nevertheless, their role in the bioaccumulation of contaminants by plants is rarely considered. Here, by comparing differences in the phyllosphere morpholog...

2025-07-16 | MTBLS12464 | MetaboLights
MetabolomicsMultiomic analysis revealed the potential role of rumen microbes in heat stress

Heat stress is an important issue in dairy cattle feeding management affecting summer health and economic efficiency. In recent years, global climate change has led to an increase in atmospheric CO2 content and average daily temperature, making heat stress a major challenge in dairy farming. This...

2022-08-11 | MTBLS5132 | MetaboLights
MetabolomicsInvolvement of the Gut Microbes Romboutsia hominis and Akkermansia muciniphila in the Pathophysiology and Development of Nonalcoholic Steatohepatitis
Background Nonalcoholic steatohepatitis (NASH) represents a growing global health challenge due to its propensity to progress to irreversible hepatic disorders, including fibrosis, cirrhosis, and carcinoma. This study aimed to investigate the role of gut microbiota in the pathogenesis of NASH. We ha...
2025-06-23 | MTBLS12631 | MetaboLights
MetabolomicsDistinct microbes, metabolites, and the host genome define the multi-omics profiles in right-sided and left-sided colon cancer

BACKGROUND: Studies have reported clinical heterogeneity between right-sided colon cancer (RCC) and left-sided colon cancer (LCC). However, none of these studies used multi-omics analysis combining genetic regulation, microbiota and metabolites to explain the site-specific differ...

2024-12-16 | MTBLS10232 | MetaboLights
MetabolomicsMetabolic changes of Fusobacterium nucleatum when co-cultured with other oral microbes (part-I)
Not available
ORGANISM(S): Fusobacterium nucleatum subsp. nucleatum ATCC 25586 
ST001260 | MetabolomicsWorkbench
MetabolomicsMetabolic changes of culture supernatants of Fusobacterium nucleatum co-cultured with other oral microbes (part-II)
Not available
ORGANISM(S): Fusobacterium nucleatum 
ST001261 | MetabolomicsWorkbench
MetabolomicsLinking bacterial metabolites to disease-associated microbes to uncover mechanisms of host-microbial interactions in intestinal inflammation. Human stool profiling
Not available
ORGANISM(S): Homo sapiens 
ST002471 | MetabolomicsWorkbench
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