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GenomicsEffect of proteases on soil
Effect of proteases on soil: Bioestimulation and Microbial Biodiversity
PRJEB35654 | ENA
ProteomicsA combined metaproteomics and metabolomics approach for the in vivo analysis of cystic fibrosis sputum focusing on microbial pathogens
Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene. This paves the way for the colonization by microbial pathogens and the concomitant establishment of chronic inf...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025134 | Pride
Sputum Microbiome 16s sequencing Metabolomics In vivo Microbial community Cystic fibrosis Metaproteomics 
ProteomicsThe secreted proteases Aur, ScpA, SspA and SspB suppress virulence of Staphylococcus aureus USA300 by shaping the extracellular proteome
Surface-located and secreted virulence factors of the Gram-positive bacterial pathogen Staphylococcus aureus are key drivers for infection of the human host. Proteolytic enzymes may contribute to virulence by breaking primary barriers and host immune defenses. Therefore, the objective of our present...
ORGANISM(S): Staphylococcus aureus 
2025-04-22 | PXD056653 | Pride
Staphylococcus aureus  virulence  proteases  peptidoglycan hydrolase  cell lysis 
ProteomicsCoMPaseD - Protease Score Prediction for the Analysis of Small Proteins
In proteome studies, the application of alternative proteases, exclusively or in addition to trypsin, often increases protein sequence or proteome coverage. It has recently been shown that, in particular, the analysis of small proteins benefits from such multi-protease approaches. In the accompanyin...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2026-01-23 | PXD062213 | Pride
Bacillus subtilis Orbitrap elite Alternative proteases Gluc Lysarginase 
UnknownRepurposing proteases: An in-silico analysis of the binding potential of extracellular fungal proteases with selected viral proteins.
Not available
S-EPMC8245309 | biostudies-literature
ProteomicsAdaptation of a microbial community to demand-oriented biological methanation
Background: Biological conversion of the surplus of renewable electricity to CH4 could support energy storage and strengthen the power grid. Biological methanation (BM) is closely linked to the activity of biogas-producing bacterial community and methanogenic Archaea in particular. During reactor o...
ORGANISM(S): Escherichia coli 
2023-03-11 | PXD034618 | Pride
Biogas upgrade Biological methanation Hydrogen starvation Renewable energy Hydrogenotrophic methanogens Acetoclastic methanogens Power to methane Microbial food-web Metaproteomics 
UnknownGut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome.
Not available
S-EPMC9081267 | biostudies-literature
UnknownStructure-Function Characteristics of SARS-CoV-2 Proteases and Their Potential Inhibitors from Microbial Sources.
Not available
S-EPMC8706127 | biostudies-literature
UnknownDiversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases.
Not available
S-EPMC4542243 | biostudies-literature
ProteomicsN-terminomics/TAILS profiling of proteases and their substrates in ulcerative colitis
Dysregulated protease activity is often implicated in the initiation of inflammation and immune cell recruitment in gastrointestinal inflammatory diseases. Using N-terminomics/TAILS (terminal amine isotopic labeling of substrates), we compared proteases, along with their substrates and inhibitors, b...
ORGANISM(S): Homo sapiens (Human) 
2019-09-08 | PXD014479 | Pride
Protease Biopsies Ulcerative colitis Tails 
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