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MetabolomicsMetabolomics of murine embryos cultured in a microfluidic device and comparison with traditional microdrops culture
Not available
ORGANISM(S): Mus musculus 
ST001494 | MetabolomicsWorkbench
MetabolomicsOrganotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations
BACKGROUND: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation; this harsh microenvironment promotes genomic in...
2019-02-08 | MTBLS669 | MetaboLights
ProteomicsPepS: a microfluidic device to process whole blood at bedside for plasma proteomic analyses
Immunoassays have been used for decades in clinical laboratories to quantify proteins in serum/plasma samples. However, different limitations hinder their use in some cases. Mass spectrometry (MS)-based proteomics analysis has recently appeared as a promising option to assess panels of protein bioma...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD019403 | Pride
Human Microfluidic device Plasma Centrifugation Dda 
TranscriptomicsMicrofluidic platform for monitoring Saccharomyces cerevisiae mutation accumulation assay
Saccharomyces cerevisiae wildtype (YPH) and ung1-deleted strains were cultivated in mutation accumulation experiments over several bottlenecks (0-50-100-150). Two different cutlure systems were used either (i) using random colony selection and plating on petri dish (classical); or (ii) a microfluidi...
ORGANISM(S): Saccharomyces cerevisiae S288C 
2021-08-01 | E-MTAB-10259 | biostudies-arrayexpress
ProteomicsCombination of a microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro model to recapitulate human brain development and neurological diseases. However, the current systems for brain organoid culture require further improvement for the reliable production of high-quality organo...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Sus scrofa domesticus (domestic pig) 
2021-06-02 | PXD025397 | Pride
Brain extracellular matrix Microfluidic device Organoid 
TranscriptomicsMicrofluidic single-cell whole-transcriptome sequencing
Single-cell whole-transcriptome analysis is a powerful tool for quantifying gene expression heterogeneity in populations of cells. Many techniques have, thus, been recently developed to perform transcriptome sequencing (RNA-Seq) on individual cells. To probe subtle biological variation between sampl...
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-47835 | biostudies-arrayexpress
GenomicsA diffusion-based microfluidic device for single-cell RNA-seq
A diffusion-based microfluidic device for single-cell RNA-seq
PRJNA488637 | ENA
TranscriptomicsEffects of Escherichia coli global gene expression due to microfluidic processing
Investigation in bacterial transcriptomics is widely used to investigate gene regulation, bacterial susceptibility to antibiotics, host-pathogen interactions, and pathogenesis. Transcriptomics is crucially dependent on suitable methods to isolate and detect bacterial RNA. Microfluidic approaches off...
ORGANISM(S): Escherichia coli CFT073 
2016-04-01 | E-GEOD-68064 | biostudies-arrayexpress
TranscriptomicsA diffusion-based microfluidic device for single-cell RNA-seq
Microfluidic devices provide a low-input and efficient platform for single-cell RNA-seq (scRNA-Seq). Here we present microfluidic diffusion-based RNA-seq (MID-RNA-seq) for conducting scRNA-seq with a diffusion-based reagent swapping scheme. This device incorporates cell trapping, lysis, reverse tran...
ORGANISM(S): Homo sapiens Mus musculus 
2019-02-25 | GSE119271 | GEO
GenomicsA microfluidic device for epigenomic profiling using 100 cells
A microfluidic device for epigenomic profiling using 100 cells
PRJNA274262 | ENA
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