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ProteomicsmicroRNA-140 inhibits inflammation and stimulates chondrogenesis in a model of IL1β-induced osteoarthritis
Osteoarthritis is a devastating disease of articular cartilage. The pathogenic factors contributing to this disorder are inflammation, extracellular matrix degradation and failure to rebuild the articular cartilage. Preclinical studies suggest that microRNA-140 (miR-140) may play a protective role i...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD003362 | Pride
Il1b Osteoarthritis Microrna-140 Inflammation Articular cartilage 
UnknownMelatonin Prevents Osteoarthritis-Induced Cartilage Degradation via Targeting MicroRNA-140.
Not available
S-EPMC6935446 | biostudies-literature
UnknownMicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
Not available
S-EPMC5862396 | biostudies-literature
GenomicsProfiling microRNA expression in murine bone healing and nonunion formation: Role of miR-140 during the early stage of bone healing
Although cellular and molecular mechanisms during the course of bone healing have been thoroughly investigated, the regulation of gene expression by microRNA during bone regeneration is still poorly understood. We hypothesized that nonunion formation is associated with different microRNA expression ...
ORGANISM(S): Mus musculus 
2019-06-27 | GSE133243 | GEO
GenomicsProfiling microRNA expression in murine bone healing and nonunion formation: Role of miR-140 during the early stage of bone healing
Profiling microRNA expression in murine bone healing and nonunion formation: Role of miR-140 during the early stage of bone healing
PRJNA550438 | ENA
UnknownmicroRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis.
Not available
S-EPMC5095680 | biostudies-literature
UnknownAnalyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level.
Not available
S-EPMC2822914 | biostudies-literature
UnknownGain-of-function mutation of microRNA-140 in human skeletal dysplasia.
Not available
S-EPMC6622181 | biostudies-literature
UnknownMicroRNA-140-3p alleviates intervertebral disc degeneration via KLF5/N-cadherin/MDM2/Slug axis.
Not available
S-EPMC8632136 | biostudies-literature
UnknownRWR-algorithm-based dissection of microRNA-506-3p and microRNA-140-5p as radiosensitive biomarkers in colorectal cancer.
Not available
S-EPMC7655152 | biostudies-literature
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