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ProteomicsProteomic characterisation of microtubule-dependent modulation of adhesion complexes
Investigating the effect of microtubule disruption by nocodazole treatment on isolated adhesion complexes.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079926 | MassIVE
GenomicsRREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [ChIP-seq]
RREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [ChIP-seq]
PRJNA928722 | ENA
ProteomicsInsulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-End Tracking Protein Network in Adipocytes
Insulin-stimulated glucose uptake is known to involve microtubules, although the function of microtubules and the microtubule-regulating proteins involved in insulin action are poorly understood. CLASP2, a plus-end tracking microtubule-associated protein (+TIP) that controls microtubule dynamics, wa...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2019-06-13 | PXD011431 | Pride
Clasp2 g2l1 insulin microtubules 
GenomicsRREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [ChIP-seq]
RREB1 regulates neuronal proteostasis and the microtubule network
ORGANISM(S): Mus musculus 
2024-01-01 | GSE223878 | GEO
GenomicsRREB1 Regulates Neuronal Proteostasis and Microtubule Network Function
RREB1 Regulates Neuronal Proteostasis and Microtubule Network Function
PRJNA928716 | ENA
GenomicsRREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [RNA-seq]
RREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [RNA-seq]
PRJNA928721 | ENA
ProteomicsKinetochores read detyrosinated tubulin to sustain microtubule attachments
Post-translational cycles of α-tubulin detyrosination/tyrosination generate microtubule diversity, with broad physiological and clinical implications. However, the mechanistic understanding of how this microtubule diversity is decoded into specific cellular functions remains largely unknown. Here we...
ORGANISM(S): Homo sapiens (Human) 
2024-10-03 | PXD047133 | Pride
Kinetochore microtubule attachments Tubulin detyrosination/tyrosination code Kmn complex 
GenomicsKATNAL2 Dysfunction Impairs Microtubule Dynamics and Contributes to Syndromic Neurodevelopmental Disease
KATNAL2 Dysfunction Impairs Microtubule Dynamics and Contributes to Syndromic Neurodevelopmental Disease
PRJNA1525560 | ENA
UnknownEffects of microtubule length and crowding on active microtubule network organization.
Not available
S-EPMC9958361 | biostudies-literature
ProteomicsA network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth
Cilia are essential motile or sensory organelles found on many eukaryotic cells. Their formation and function rely on axonemal microtubules, which exhibit very slow dynamics, however the underlying biochemical mechanisms are largely unexplored. Here, we reconstituted in vitro the individual and coll...
ORGANISM(S): Homo sapiens (Human) 
2024-11-19 | PXD055631 | Pride
Mt dynamics Microtubles Ip-ms Cell biology 
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