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Objective: Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse genes are shared in the human, so these stu...
ORGANISM(S): Mus musculus 
Objective: Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse genes are shared in the human, so these stu...
ORGANISM(S): Mus musculus 
* Bone signaling in middle ear development *
Common middle ear diseases, such as chronic suppurative otitis media and cholesteatoma, may affect bone behavior in the middle ear air cell system.
This study analyzed gene expression of bone-related signaling factors and gene sets from lini...
ORGANISM(S): Rattus norvegicus 
Chronic Otitis Media (OM) develops after sustained inflammation and is characterized by secretory middle ear epithelial metaplasia and effusion, most frequently mucoid. Non-typeable Haemophilus influenzae (NTHi), the most common acute OM pathogen, is known to activate inflammation and mucin expressi...
ORGANISM(S): Mus musculus 
Objective: Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse genes are shared in the human, so these stu...
ORGANISM(S): Mus musculus 
2013-07-23 | GSE49128 | GEO
N6-methyladenosine methylation landscape of human normal skin and middle ear cholesteatoma
The transcriptional landscape of the murine middle ear epithelium in vitro
Microarray analysis and functional prediction of differentially-expressed circular RNAs in acquired middle ear cholesteatoma
Single-cell transcriptomes reveal a complex cellular landscape in the middle ear and differential capacities for acute response to infection gene expression by cell types in the middle ear
NTHi bacteria or saline were inoculated into the middle ears of mice. Mice were sacrificed at various times to monitor the course of infection. We used Mouse430_2 arrays to profile gene expression in response to bacterial infection RNA extracted at sacrifice
ORGANISM(S): Mus musculus 
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