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ProteomicsProject Name: Functional proteomics of midostaurin in lung cancer cells: Chemical Proteomics
Lung cancer is associated with high prevalence and mortality, and despite significant successes with targeted drugs in genomically defined subsets of lung cancer and immunotherapy, the majority of patients currently does not benefit from these therapies. Through a targeted drug screen, we found the ...
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD010787 | Pride
Drug pulldown Midostaurin Chemical proteomics Lung cancer 
ProteomicsFunctional proteomics of midostaurin in lung cancer cells: IMAC Phosphoproteomics
Lung cancer is associated with high prevalence and mortality, and despite significant successes with targeted drugs in genomically defined subsets of lung cancer and immunotherapy, the majority of patients currently does not benefit from these therapies. Through a targeted drug screen, we found the ...
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD010786 | Pride
Phosphoproteomics Lung cancer Midostaurin 
ProteomicsFunctional proteomics of midostaurin in lung cancer cells: Phosphotyrosine Profiling
Lung cancer is associated with high prevalence and mortality, and despite significant successes with targeted drugs in genomically defined subsets of lung cancer and immunotherapy, the majority of patients currently does not benefit from these therapies. Through a targeted drug screen, we found the ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-03 | PXD009041 | Pride
Tyrosine phosphorylation Midostaurin Lung cancer 
GenomicsRNA-seq of CT26 cells and tumors treated with or without Midostaurin
RNA-seq of CT26 cells and tumors treated with or without Midostaurin
PRJNA1422245 | ENA
UnknownInvestigation into CYP3A4-mediated drug-drug interactions on midostaurin in healthy volunteers.
Not available
S-EPMC3834177 | biostudies-literature
UnknownMidostaurin: an emerging treatment for acute myeloid leukemia patients.
Not available
S-EPMC4848023 | biostudies-literature
UnknownMidostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study.
Not available
S-EPMC6591272 | biostudies-literature
UnknownMidostaurin potentiates rituximab antitumor activity in Burkitt's lymphoma by inducing apoptosis.
Not available
S-EPMC6315025 | biostudies-literature
UnknownMidostaurin, bortezomib and MEC in relapsed/refractory acute myeloid leukemia.
Not available
S-EPMC5360182 | biostudies-literature
UnknownMidostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation.
Not available
S-EPMC5754190 | biostudies-literature
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