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TranscriptomicsOryza sativa Transcriptome or Gene expression
To investigate impacts of genome-wide loss of Cytosine methylation at CG sites (mCs) on global expression of protein-coding genes (henceforth referring to genes), we conducted deep RNA-seq analysis on OsMET1-2−/− relative to its sibling WT and heterozygote (OsMET1-2+/−), each with two biologic...
ORGANISM(S): Oryza sativa 
2014-08-09 | E-MTAB-4224 | biostudies-arrayexpress
TranscriptomicsAlterations to the Synaptic Transcriptome in Response to Ethanol-Induced Behavioral Sensitization in DBA/2J Mice
Alcoholism is a complex neurological disorder characterized by loss of control in limiting intake, and progressive compulsion to seek and consume ethanol. Prior studies have suggested that the characteristic behaviors associated with escalation of drug use are caused, at least in part, by ethanol-ev...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-73018 | biostudies-arrayexpress
TranscriptomicsDifferential analysis of GM-CSF-induced inflammatory monocyte-derived cells (MCs) isolated from various organs
Elevated frequencies of GM-CSF-producing helper T (TH) cells are consistently found in multiple sclerosis (MS) patients and GM-CSF expression is a non-redundant feature of pathogenic TH cells in preclinical models of MS. GM-CSF activates an inflammatory signature in monocytes, and their progeny are ...
ORGANISM(S): Mus musculus 
2017-02-21 | E-MTAB-5412 | biostudies-arrayexpress
TranscriptomicsFormaldehyde exposure alters miRNAs expression profiles in olfactory bulb
Neurotoxicity of formaldehyde (FA) in the human health attracted intensive studies Long-term exposure to FA leads to learning and memory decline and is responsible for the multiple chemical sensitivity (MCS) or sick building syndrome (SBS). It was cleared that Formaldehyde impairs Learning and Memor...
ORGANISM(S): Mus musculus 
2015-08-04 | E-GEOD-59369 | biostudies-arrayexpress
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