Sort   by:  
 Page size 
ProteomicsProteomic Characterization of Human Milk Fat Globule Membrane Proteins during a 12 Month Lactation Period
The milk fat globule membrane (MFGM) contains proteins which have been implicated in a variety of health benefits. Milk fat globule membrane proteins were isolated from human milk during a 12 month lactation period and subjected to in solution digestion and liquid chromatography tandem mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-24 | MSV000089722 | MassIVE
ProteomicsXanthine Oxidoreductase mediates milk fat globule secretion.
Analysis of the milk fat globule proteome from mice with a mammary-specific knockout of Xanthine Oxidoreductase.
ORGANISM(S): Mus musculus (Mouse) 
2017-05-31 | PXD003336 | Pride
Apocrine secretion Xanthine oxidoreductase Proteomics Lactation Lipid droplet Mouse Milk fat globule Lc-ms/ms 
ProteomicsA proteomic characterization reveals differences in the milk fat globule membrane of buffalo and bovine milk
The proteins of the milk fat globule membrane (MFGM) have a number of functions, such as the regulation of milk fat secretion and metabolism, the uptake and transportation of fatty acids in the intestine and potential protection from bacterial or viral infection. While the proteome of the MFGM in bo...
ORGANISM(S): Bos taurus (Bovine) Bubalus bubalis 
2017-05-19 | PXD005318 | Pride
Xanthine oxidase Proteomics Buffalo milk Milk fat globule membrane Lc-ms/ms 
TranscriptomicsGene Expression in the Human Mammary Epithelium during Lactation: the Milk Fat Globule Transcriptome through 4 Days
The 4 day gene expression profile in the lactating mammary gland was demonstrated using the Human Ref-8 BeadChip array (Illumina, Inc). Of the 22,184 gene transcripts on the array, 14,070 genes were consistently expressed and represented the milk fat globule transcriptome. Milk protein genes were am...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-15208 | biostudies-arrayexpress
ProteomicsPerilipin 2 mediates milk fat globule secretion
Analysis of the milk fat globule membrane proteome from mice with genetic deletion of Perilipin 2 (Plin2/ADRP/ADPH)
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD035020 | Pride
Adrp Perilipin 2 Apocrine secretion Lc ms/ms Proteomics Lactation Lipid droplet Adph Mouse Milk fat globule membrane 
TranscriptomicsGene Expression in the Human Mammary Epithelium in response to consumption of high fat (H-FAT) and high carbohdyrate (H-CHO) diets.
Mammary gland (MG) de novo lipogenesis contributes significantly to milk fat in animals but little is known in humans. We hypothesized that de novo lipogenesis, as reflected by incorporation of 13C carbons from [U-13C]glucose into fatty acids (FAs) and glycerol in triglycerides (TG), will be greate...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-51874 | biostudies-arrayexpress
ProteomicsProteomics of the Milk Fat Globule Membrane from Camelus dromedarius
Camel milk is widely characterized with regard to caseins and whey proteins. However, in camelids, close to nothing is known about the Milk Fat Globule Membrane (MFGM), the membrane surrounding fat globules in milk. The purpose of this study was thus to identify MFGM proteins from Camelus dromedariu...
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2013-02-05 | PXD000059 | Pride
Dromedarius Mfgm Ls-msms 
ProteomicsThe plasma membrane, casein-containing vesicles and endoplasmic reticulum are the main membrane contributors to milk fat globule membrane formation
During lactation, mammary epithelial secretory cells secrete huge amounts of milk from their apical side. The major milk proteins, the caseins, are secreted by exocytosis, while milk fat globules are released by budding, enwrapped by the plasma membrane. Due to the number and large size of milk fat ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-19 | PXD001024 | Pride
Mouse Mfgm Lc-ms/ms 
TranscriptomicsElevated dairy fat intake in lactating women alters milk lipid and fatty acids without detectible changes in expression of genes related to lipid uptake or synthesis
Previous work has demonstrated that elevated maternal lipid intake (particularly from dairy products) is associated with increased lipids and altered fatty acid profile in milk produced by healthy lactating women. We investigate our primary hypothesis that a maternal diet rich in full-fat dairy prod...
ORGANISM(S): Homo sapiens 
2015-02-24 | E-GEOD-66191 | biostudies-arrayexpress
ProteomicsPhosphoproteomics of the Milk Fat Globule Membrane: new insights into lipid droplet secretion from the mammary epithelial cell
Lipid droplets are secreted into milk by a complex process which begins by burgeoning oflipids at the endoplasmic reticulum of the mammary epithelial cell (MEC). Lipid dropletsenveloped by organelle-derived phospholipids reach the apical pole of the cell where they arewrapped by t...
ORGANISM(S): Capra hircus (Goat) 
2015-05-12 | PXD001039 | Pride
Mammary epithelial cell Secretion Phosphoproteome Milk Lipid droplet 
Sort   by:  
 Page size