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ProteomicsProteomic Characterization of Human Milk Fat Globule Membrane Proteins during a 12 Month Lactation Period
The milk fat globule membrane (MFGM) contains proteins which have been implicated in a variety of health benefits. Milk fat globule membrane proteins were isolated from human milk during a 12 month lactation period and subjected to in solution digestion and liquid chromatography tandem mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-24 | MSV000089722 | MassIVE
ProteomicsXanthine Oxidoreductase mediates milk fat globule secretion.
Analysis of the milk fat globule proteome from mice with a mammary-specific knockout of Xanthine Oxidoreductase.
ORGANISM(S): Mus musculus (Mouse) 
2017-05-31 | PXD003336 | Pride
Apocrine secretion Xanthine oxidoreductase Proteomics Lactation Lipid droplet Mouse Milk fat globule Lc-ms/ms 
ProteomicsA proteomic characterization reveals differences in the milk fat globule membrane of buffalo and bovine milk
The proteins of the milk fat globule membrane (MFGM) have a number of functions, such as the regulation of milk fat secretion and metabolism, the uptake and transportation of fatty acids in the intestine and potential protection from bacterial or viral infection. While the proteome of the MFGM in bo...
ORGANISM(S): Bos taurus (Bovine) Bubalus bubalis 
2017-05-19 | PXD005318 | Pride
Xanthine oxidase Proteomics Buffalo milk Milk fat globule membrane Lc-ms/ms 
ProteomicsPerilipin 2 mediates milk fat globule secretion
Analysis of the milk fat globule membrane proteome from mice with genetic deletion of Perilipin 2 (Plin2/ADRP/ADPH)
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD035020 | Pride
Adrp Perilipin 2 Apocrine secretion Lc ms/ms Proteomics Lactation Lipid droplet Adph Mouse Milk fat globule membrane 
ProteomicsThe plasma membrane, casein-containing vesicles and endoplasmic reticulum are the main membrane contributors to milk fat globule membrane formation
During lactation, mammary epithelial secretory cells secrete huge amounts of milk from their apical side. The major milk proteins, the caseins, are secreted by exocytosis, while milk fat globules are released by budding, enwrapped by the plasma membrane. Due to the number and large size of milk fat ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-19 | PXD001024 | Pride
Mouse Mfgm Lc-ms/ms 
ProteomicsProteomics of the Milk Fat Globule Membrane from Camelus dromedarius
Camel milk is widely characterized with regard to caseins and whey proteins. However, in camelids, close to nothing is known about the Milk Fat Globule Membrane (MFGM), the membrane surrounding fat globules in milk. The purpose of this study was thus to identify MFGM proteins from Camelus dromedariu...
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2013-02-05 | PXD000059 | Pride
Dromedarius Mfgm Ls-msms 
ProteomicsPhosphoproteomics of the Milk Fat Globule Membrane: new insights into lipid droplet secretion from the mammary epithelial cell
Lipid droplets are secreted into milk by a complex process which begins by burgeoning oflipids at the endoplasmic reticulum of the mammary epithelial cell (MEC). Lipid dropletsenveloped by organelle-derived phospholipids reach the apical pole of the cell where they arewrapped by t...
ORGANISM(S): Capra hircus (Goat) 
2015-05-12 | PXD001039 | Pride
Mammary epithelial cell Secretion Phosphoproteome Milk Lipid droplet 
GenomicsMilk fat globule membrane modulates inflammatory pathways in human monocytes: A crossover human intervention study
Milk fat globule membrane modulates inflammatory pathways in human monocytes: A crossover human intervention study
PRJNA1050584 | ENA
TranscriptomicsRole of milk fat globule membrane (MFGM) in modulating gene expression in humans
The aim of this study was to investigate if milk fat globule membrane (MFGM) enclosing the dairy fat influence peripheral blood mononuclear cells (PBMC) gene expression. This study was a 8-week single-blind, randomized, controlled isocaloric trial with two parallel groups including overweight (mean ...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-60148 | biostudies-arrayexpress
TranscriptomicsMilk fat globule membrane modulates inflammatory pathways in human monocytes: A crossover human intervention study
Intake of high-fat foods raises postprandial plasma triglycerides and inflammatory markers, which may depend on the type of fat ingested. Dairy products are commonly consumed, but not much is known about the impact of milk fat and the milk fat globule membrane on postprandial inflammation. Here, we ...
ORGANISM(S): Homo sapiens 
2023-12-09 | GSE249787 | GEO
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