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MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
ProteomicsWhole milk proteome of human and rhesus macaque during peak lactation
Milk has been well established as the optimal nutrition source for infants, yet there is still much to be understood about its molecular composition. Therefore, our objective was to develop and compare comprehensive milk proteomes for human and rhesus macaques to highlight differences in neonatal nu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Macaca Mulatta (ncbitaxon:9544) 
2015-02-23 | MSV000079045 | MassIVE
ProteomicsProteomic Profiling of Donkey Milk Exosomes Highlights Bioactive Proteins with Immune-Related Functions
Proteomic profiles of exosomes isolated from donkey colostrum and mature milk using advanced four-dimensional (4D) label-free quantitative proteomics. A comprehensive analysis identified and quantified a total of 2,293 exosomal proteins from donkey milk, including 276 differentially expressed exosom...
ORGANISM(S): Equus Asinus X Caballus 
2025-03-18 | PXD061958 |
ProteomicsAntibody-independent identification of bovine milk-derived peptides in breast-milk
Exclusively breast-fed infants can exhibit clear signs of IgE or non IgE-mediated cow’s milk allergy. The definite characterization of dietary cow’s milk proteins (CMP) that survive the maternal digestive tract to be absorbed into the bloodstream and secreted into breast milk remains missing. The ai...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080880 | MassIVE
ProteomicsProteomics Analysis of Human Breast Milk to Assess Breast Cancer Risk
Detection of breast cancer (BC) in young women is challenging because mammography, the most common tool for detecting BC, is not effective on the dense breast tissue characteristic of young women. In addition to the limited means for detecting their BC, young women face a transient increased risk of...
ORGANISM(S): Homo sapiens (Human) 
2017-12-18 | PXD007066 | Pride
Mass spectrometry Breast cancer Breast milk Proteomics Biomarkers 
Proteomicsmilk-derived extracellular vesicles UHPLC-MS
Breast milk contains macromolecular components with distinctive functions, whereby milk fat globules and casein micelles provide nutrition, while whey contains molecules that stimulate the infant’s immunity. Interestingly, the importance and function of extracellular vesicles (EV) in milk has not be...
ORGANISM(S): Homo sapiens (Human) 
2016-09-27 | PXD004423 | Pride
Lc-ms Human milk Vesicles Milk proteome 
ProteomicsAntibody-independent identification of bovine milk-derived peptides in breast-milk
Exclusively breast-fed infants can exhibit clear signs of IgE or non IgE-mediated cow’s milk allergy. The definite characterization of dietary cow’s milk proteins (CMP) that survive the maternal digestive tract to be absorbed into the bloodstream and secreted into breast milk remains missing. The ai...
ORGANISM(S): Homo sapiens (Human) 
2016-07-19 | PXD003657 | Pride
Bovine Peptides Human Milk Lc-ms/ms 
ProteomicsHeat-treatments affect protease activities and peptide profiles of ruminants’ milk
Proteases present in milk are heat-sensitive, and their activities increase or decrease depending on the intensity of the thermal treatment applied. The thermal effects on the protease activity are well-known for bovine milk but poorly understood for ovine and caprine milk. This study aimed to deter...
ORGANISM(S): Bos taurus (Bovine) 
2021-09-09 | PXD022702 | Pride
Peptidomics Milk 
ProteomicsProteomics of Human Milk: Definition of a Discovery Workflow for Clinical Research Studies
Proteins in milk have been studied for decades and proteomics, peptidomics, and glycoproteomics are the main approaches previously deployed to decipher the proteome of human milk. In the present work, we aimed at implementing a highly automated pipeline for the proteomic analysis of human milk with ...
ORGANISM(S): Homo sapiens (Human) 
2021-08-01 | PXD021974 | Pride
Human Shotgun Milk Proteomics Lc-ms/ms 
ProteomicsDiscovery-driven target selection from six milk-derived ingredients for consensus detection of casein and whey milk allergens
Milk is one among the most common food allergens and the proteins representing caseins and whey fractions of milk have been characterized as the major triggers for allergic responses in susceptible individuals. Milk or milk-derived ingredients- varying in their casein and whey protein content and co...
ORGANISM(S): Bos taurus (Bovine) 
2020-06-05 | PXD016429 | Pride
Milk allergen detection  casein allergen  whey allergen  thermal processing  prm 
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