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MetabolomicsLipid profile analysis of donkey milk during the lactation

Background: From ancient times, donkey milk (DM) has attracted much attention due to its particular properties. Donkey milk is characterized by a high level of lactose and low levels of protein and fat. However, studies investigating lipid changes in donkey milk during lactation are limited....

2025-09-06 | MTBLS12948 | MetaboLights
ProteomicsPhosphoproteomics of the Milk Fat Globule Membrane: new insights into lipid droplet secretion from the mammary epithelial cell
Lipid droplets are secreted into milk by a complex process which begins by burgeoning oflipids at the endoplasmic reticulum of the mammary epithelial cell (MEC). Lipid dropletsenveloped by organelle-derived phospholipids reach the apical pole of the cell where they arewrapped by t...
ORGANISM(S): Capra hircus (Goat) 
2015-05-12 | PXD001039 | Pride
Mammary epithelial cell Secretion Phosphoproteome Milk Lipid droplet 
TranscriptomicsUnique microRNA profiles revealed in different fractions of human milk and maternal blood during lactation
Human milk (breastmilk) is much more than nutrition for the infant, containing an array of regulatory agents with immunoprotective and developmental functions. Amongst those, microRNAs (miRNAs) have recently been identified, with their properties, roles, origin and distribution in breastmilk as well...
ORGANISM(S): Glycine max 
2015-03-30 | E-GEOD-66358 | biostudies-arrayexpress
TranscriptomicsGene expression of lipid metabolism-related genes correlated with milk fatty acids in dairy cows
The aim of the present study was to correlate lipid metabolism genes in the mammary gland tissue affected by stage of lactation and nutrition to the resulting milk fatty acids composition in grazing dairy cows, and to classify milk fatty acid (FA) groups based on variations in lipid metabolism gene ...
ORGANISM(S): Bos taurus 
2011-01-01 | E-GEOD-20908 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mammary gland at key stages in development
The transition from pregnancy to lactation is a critical event in the survival of the newborn since all the nutrient requirements of the infant are provided by milk. While milk contains numerous components, including proteins, that aid in maintaining the health of the infant, lactose and milk fat re...
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-8191 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver and mammary gland from lactating or pregnant animals fed on low or high energy diets to test the hypothesis that multiple metabolic control points and potential regulatory mechanisms are involved in activating lipid and lactose synthesis at the onset of lactation
The mammary gland of the lactating mouse synthesizes and secretes milk lipid equivalent to its entire body weight in a single 20 day lactation cycle, making it one of the most active lipid synthetic organs known. To test the hypothesis that multiple metabolic control points and potential regulatory ...
ORGANISM(S): Mus musculus 
2007-12-12 | E-GEOD-4222 | biostudies-arrayexpress
UnknownTDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh.
Not available
S-EPMC6969145 | biostudies-literature
UnknownA test of current models for the mechanism of milk-lipid droplet secretion.
Not available
S-EPMC4524534 | biostudies-literature
TranscriptomicsComparison of Differences in Mouse Mammary gland gene expression data at POSTNATAL DAY 70 in Akt1wildtype versus Akt1-deficient mice
Akt1, a serine-threonine protein kinase member of the PKB/Akt gene family, plays a critical role in the regulation of several cellular processes including cell proliferation and apoptosis. In this study, we utilized Akt1+/+ and Akt1¬-/- C57/Bl6 female mice to demonstrate that Akt1 is required for n...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30671 | biostudies-arrayexpress
TranscriptomicsMammary gene expression profile of goats receiving high or low forage diets supplemented or not with lipids
Animal nutrition considerably affects milk composition that influences its nutritional quality. Milk component synthesis and secretion by the mammary gland involve the expression of a large number of genes whose nutritional regulation remains poorly defined. In this study, 16 lactating goats receive...
ORGANISM(S): Capra hircus 
2009-11-29 | E-GEOD-11592 | biostudies-arrayexpress
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