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TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
TranscriptomicsGenomic expression over batch growth of mupirocin producing strain Pseudomonas synxantha NCIMB10586
The Pseudomonas synxantha strain NCIMB10586 produces the antibiotic mupirocin / Pseudomonic acid A from a 75 kb gene cluster; expression of this is regulated through quorum-sensing. We wished to examine expression of the strain during batch growth, in particular of the mupirocin cluster and any othe...
ORGANISM(S): Pseudomonas synxantha 
2021-06-04 | E-MTAB-10255 | biostudies-arrayexpress
TranscriptomicsThe ACME and SCCmec Linkage of Virulence with Resistance in the Community Methicillin Resistant S. aureus USA300 Clone
The epidemic character of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA), especially the geographically widespread clone USA300, is poorly understood. USA300 isolates carry a type IV staphylococcal chromosomal cassette mec (SCCmec) element conferring -lactam antibiotic ...
ORGANISM(S): Staphylococcus aureus 
2010-05-19 | E-GEOD-9308 | biostudies-arrayexpress
TranscriptomicsPrenatal Arsenic Exposure Alters Gene Expression in the Adult Liver to a Proinflammatory State Contributing to Accelerated Atherosclerosis
Developmental exposures play a role in adult onset chronic disease. The mechanisms by which environmental toxicants alter developmental processes predisposing individuals to chronic disease are not understood. arsenic exposure via drinking water causes cancer and cardiovascular disease. Transplacent...
ORGANISM(S): Mus musculus 
2012-06-21 | E-GEOD-30783 | biostudies-arrayexpress
UnknownBiological and therapeutic implications of multisector sequencing in newly diagnosed glioblastoma.
Not available
S-EPMC5909635 | biostudies-literature
UnknownFormation of an ion-free crystalline carbon nitride and its reversible intercalation with ionic species and molecular water.
Not available
S-EPMC6385848 | biostudies-literature
UnknownA Need for Strategies to Reduce Alcohol Use After Metabolic and Bariatric Surgery: Technology-Based Intervention and Study Protocol for a Pilot Randomized Controlled Trial.
Not available
S-EPMC12824574 | biostudies-literature
UnknownAquaporin-like water transport in nanoporous crystalline layered carbon nitride.
Not available
S-EPMC7518864 | biostudies-literature
UnknownFactors Associated With Alcohol Use After Metabolic and Bariatric Surgery: Protocol for an Ecological Momentary Assessment.
Not available
S-EPMC12853087 | biostudies-literature
TranscriptomicsApplication of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions
Chromosomal instability is central to the process of carcinogenesis. The detection of somatic chromosomal alterations in small premalignant lesions genome-wide remains challenging since sample heterogeneity dilutes the aberrant cell information. We introduced an analytic metric termed "delta-θ&...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-GEOD-43168 | biostudies-arrayexpress
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