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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsTranscription profiling of 22 Pancreatic Cancer Cell Lines
We used microarrays to analyze the global expression patterns for 22 commercially available pancreatic cancer cell lines 22 pancreatic cancer cell lines were grown to 80% confluence in DMEM/FBS/PenStrep media and then harvested for total RNA
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21654 | biostudies-arrayexpress
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of genomic DNA from two B. bronchiseptica strains and one B. pertussis strain and sequenced reference genomes by comparative genome hybridization (CGH)
Genomic DNA from two B. bronchiseptica strains and one B. pertussis strain were compared to the sequenced reference genomes by comparative genome hybridization (CGH).
ORGANISM(S): Bordetella bronchiseptica 
2006-03-31 | E-MEXP-399 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella Bvg phase-locked mutants
bvgS phase-locked mutant derivatives of B. bronchiseptica RB50, B. pertussis GMT-1, and B. pertussis Tohama I were grown at 37 degrees C in the absence of modulator and harvested at mid-log phase. Comparison of gene expression profiles identified a set of genes in each strain that were regulated by...
ORGANISM(S): Bordetella bronchiseptica 
2006-03-31 | E-TABM-31 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella bronchiseptica RB50 nicotinic acid dose curve
B. bronchiseptica RB50 and a constitutive Bvg+ phase-locked mutant were grown at 37 degrees C in media containing a range of nicotinic acid concentrations.
ORGANISM(S): Bordetella bronchiseptica 
2006-03-31 | E-TABM-28 | biostudies-arrayexpress
UnknownInitial genome sequencing of the sugarcane CP 96-1252 complex hybrid.
Not available
S-EPMC5497815 | biostudies-literature
TranscriptomicsTranscription profiling of Bordetella pertussis GMT-1 nicotinic acid dose curve
B. pertussis GMT-1 and a constitutive Bvg+ phase-locked mutant were grown at 37 degrees C in media containing a range of nicotinic acid concentrations
ORGANISM(S): Bordetella pertussis 
2006-03-31 | E-TABM-29 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella pertussis GMT-1 magnesium sulfate shift
B. pertussis GMT-1 was grown in media containing magnesium sulfate to put the culture in the Bvg- phase. The cells were then washed and grown in media lacking magnesium sulfate and samples were harvested at time=0 and several time points beyond.
ORGANISM(S): Bordetella bronchiseptica 
2006-03-31 | E-TABM-30 | biostudies-arrayexpress
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