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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownAssessment of Primary Site Response in Children With High-Risk Neuroblastoma: An International Multicenter Study.
Not available
S-EPMC4872026 | biostudies-literature
ProteomicsTissue architectural cues mediated by integrin signaling
Analysis of human or mouse tumor cell lines that target to different organs upon extravasation
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-06-21 | MSV000084006 | MassIVE
UnknownPropofol anesthesia destabilizes neural dynamics across cortex.
Not available
S-EPMC11923585 | biostudies-literature
TranscriptomicsDynamic transcriptome analysis reveals mRNA synthesis and decay in yeast
To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA was used to monitor the cellular response to osmotic stress in comparison to the wild type. Genomic occupa...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-01 | E-MTAB-439 | biostudies-arrayexpress
TranscriptomicsTranscription of human thrombopoietin-induced megakaryocyte differentiation with and without nicotinamide vs. Universal reference sample
Culture of hematopoietic stem and progenitor cells in the presence of thrombopoietin induces megakaryocytic differentiation. Addition of nicotinamide to thrombopoietin-stimulated cultures results in significant increases in megkaryocytic differentiation including greater polyploidization and enhanc...
ORGANISM(S): Homo sapiens 
2009-04-08 | E-GEOD-4974 | biostudies-arrayexpress
UnknownSuccessful implementation of stroke risk screening for sickle cell anemia in the DISPLACE study: results of a cluster randomized trial.
Not available
S-EPMC12659106 | biostudies-literature
TranscriptomicsFormaldehyde-induced changes in microRNA signaling [Affymetrix]
In addition to gaining knowledge on in vivo miRNA responses to formaldehyde, we set out to relate these miRNA responses to transcriptional profiles modified by formaldehyde. Rats were exposed by inhalation to either 0 or 2 ppm formaldehyde (6 hours/day) for 28 days. Genome-wide transcriptional profi...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-42394 | biostudies-arrayexpress
TranscriptomicsFormaldehyde-induced changes in microRNA signaling [Agilent]
MicroRNAs (miRNAs) are critical regulators of gene expression, yet much remains unknown regarding miRNA changes resulting from environmental exposures and whether they influence pathway signaling across various tissues and time. To gain knowledge on these novel topics, we set out to investigate in v...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-42393 | biostudies-arrayexpress
UnknownOutcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward.
Not available
S-EPMC5012712 | biostudies-literature
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