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TranscriptomicsMicroarray profiling of WT or PDE10A KO mice treated with vehicle or a PDE10 inhibitor
Inhibition of phosphodiesterase 10A (PDE10A) promotes cyclic nucleotide signaling, increases striatal activation, and decreases behavioral activity. Enhanced cyclic nucleotide signaling is a well established route to producing changes in gene expression. We hypothesized that chronic suppression of P...
ORGANISM(S): Mus musculus 
2012-08-25 | E-GEOD-40377 | biostudies-arrayexpress
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S-EPMC3934929 | biostudies-literature
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