Sort   by:  
 Page size 
ProteomicsRNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism
Cancer cells rely on mitochondria for their bioenergetic supply and macromolecule synthesis. Central to mitochondrial function is the regulation of mitochondrial protein synthesis, which primarily depends on the cytoplasmic translation of nuclear-encoded mitochondrial mRNAs whose protein products ar...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD036780 | Pride
Hnrnpu  co-immunoprecipitation 
ProteomicshnRNP 1 H/F drive RNA G-quadruplex-mediated translation linked to genomic instability and therapy resistance in glioblastoma
RNA G-quadruplexes (RG4s) are four-stranded structures known to control mRNA translation of cancer relevant genes. RG4 formation is pervasive in vitro but not in cellulo, indicating the existence of a poorly characterized molecular machinery that remodels RG4s and maintains them unfolded. To help fi...
ORGANISM(S): Homo sapiens (Human) 
2020-11-11 | PXD015609 | Pride
Ap-ms Human glioblastoma G-quadruplex rna-protein interactions Orbitrap fusion 
Sort   by:  
 Page size