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TranscriptomicsHNRNPU RNA targets and DNA methylation changes during neural differentiation
This study investigates the molecular mechanisms by which the DNA/RNA-binding protein HNRNPU regulates gene expression during early human neural development. Pathogenic variants in HNRNPU cause a severe neurodevelopmental disorder, but the underlying mechanisms remain poorly understood. To explore t...
ORGANISM(S): Homo sapiens 
2026-02-02 | E-MTAB-14910 | biostudies-arrayexpress
ProteomicsProtein interactome of HNRNPU in differentiating neural cells
HNRNPU is an RNA-binding protein with diverse roles in regulating gene expression. Pathogenic genetic variants of HNRNPU cause a severe neurodevelopmental disorder (NDD), but the underlying molecular mechanisms are unclear. Here, we investigated the protein-protein interaction (PPI) network of HNRNP...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD061718 | Pride
Human Differentiation Neural cell Lc-esi-ms/ms 
GenomicsHNRNPU regulates lncRNAs nuclear localization
HNRNPU regulates lncRNAs nuclear localization
PRJNA694053 | ENA
GenomicsHNRNPU RNA targets during neural differentiation using fRIP-Seq
HNRNPU RNA targets during neural differentiation using fRIP-Seq
PRJEB86784 | ENA
GenomicsGene expression and splicing regulation by hnRNPU in skeletal muscle
Gene expression and splicing regulation by hnRNPU in skeletal muscle
PRJNA607983 | ENA
GenomicsTranscriptomic analysis of gastric cancer cells in response to stable over-expression of circRNA derived from hnRNPU (circ-hnRNPU)
Transcriptomic analysis of gastric cancer cells in response to stable over-expression of circRNA derived from hnRNPU (circ-hnRNPU)
PRJNA1034984 | ENA
GenomicsHNRNPU MY-CLIP study using cytoplasmic or whole lysates
HNRNPU MY-CLIP study using cytoplasmic or whole lysates
PRJNA576694 | ENA
ProteomicsIdentification of SAFB and HnrnpU interactors
Scaffold Attachment Factor B (SAFB) is a conserved RNA Binding Protein (RBP) that is essential for early mammalian development. However, the RNAs that associate with SAFB in mouse embryonic stem cells have not been characterized. Here, we addressed this unknown using RNA-seq and SAFB RNA immunopreci...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD038103 | Pride
Stem cell Development Rna binding proteins 
UnknownTargeting HNRNPU to overcome cisplatin resistance in bladder cancer.
Not available
S-EPMC8819945 | biostudies-literature
GenomicsHNRNPU Lactylation Drives Cervical Cancer Growth by Reprogramming Serine Metabolism
HNRNPU Lactylation Drives Cervical Cancer Growth by Reprogramming Serine Metabolism
PRJNA1455537 | ENA
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