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MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
TranscriptomicsTranscription profiling of mouse gastric epithelial cell types: parietal, zymogenic, and pit
Continuous regeneration of digestive enzyme (zymogen) secreting chief cells is a normal aspect of stomach function that is disrupted in pre-cancerous lesions. Regulation of zymogenic cell (ZC) differentiation is poorly understood. Here we profile Parietal, Pit, and Zymogenic cells for comparison an...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5018 | biostudies-arrayexpress
UnknownThe HIV Care Continuum: Changes over Time in Retention in Care and Viral Suppression.
Not available
S-EPMC4473034 | biostudies-literature
TranscriptomicsResveratrol prevents diet-induced arterial degeneration and stiffening in nonhuman primates
Cardiovascular (CV) disease is a leading cause of morbidity and mortality in Western societies. Even after accounting for traditional CV risk factors (e.g. obesity, smoking and hypertension), the inflammation-driven thickening and stiffening of central arteries is a strong predictor of adverse outco...
ORGANISM(S): Macaca mulatta 
2014-07-21 | E-GEOD-45927 | biostudies-arrayexpress
UnknownGlobal, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Not available
S-EPMC5055577 | biostudies-literature
UnknownGlobal, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Not available
S-EPMC5224694 | biostudies-literature
UnknownGlobal, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Not available
S-EPMC5224696 | biostudies-literature
UnknownEstimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
Not available
S-EPMC5056319 | biostudies-literature
UnknownGlobal, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Not available
S-EPMC5388856 | biostudies-literature
UnknownGlobal, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Not available
S-EPMC5605514 | biostudies-literature
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