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TranscriptomicsCandidate pathways for promoting differentiation and quiescence of oligodendrocyte progenitor-like cells in glioblastoma
The mature CNS contains PDGFRA+ ‘oligodendrocyte progenitor cells’ (OPC) which may remain quiescent, proliferate, or differentiate into oligodendrocytes. In human gliomas, rapidly proliferating Olig2+ cells resembling OPCs are frequently observed. We sought to identify, in vivo, candidate pathways u...
ORGANISM(S): Mus musculus 
2012-10-04 | E-GEOD-30626 | biostudies-arrayexpress
TranscriptomicsComparison of polysomal profiles of murine adult normal, tumor, and recruited olig2 cells
Comparison of polysomal profiles of murine adult olig2 cortical progenitors, murine tumor olig2 cells derived from hPDGF-B-driven glioblastomas, and murine olig2 proliferative recruited glioma cells contributing to the tumor mass but not derived from the cell of origin An unbiased way to define a c...
ORGANISM(S): Mus musculus 
2011-06-17 | E-GEOD-30016 | biostudies-arrayexpress
GenomicsChromosome 11 analysis in myeloid malignancies - WES
Blood samples from patients with myeloid malignancies were analyzed using whole exome sequencing (WES). Data set from genotyping by microarray of the same samples has been deposited in ArrayExpress under accession number E-MTAB-1845 (https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-1845/).
ORGANISM(S): Homo sapiens 
2013-11-01 | E-MTAB-1850 | biostudies-arrayexpress
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