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TranscriptomicsComparative genomic hybridization of genomic DNA from two B. bronchiseptica strains and one B. pertussis strain and sequenced reference genomes by comparative genome hybridization (CGH)
Genomic DNA from two B. bronchiseptica strains and one B. pertussis strain were compared to the sequenced reference genomes by comparative genome hybridization (CGH).
ORGANISM(S): Bordetella bronchiseptica 
2006-03-31 | E-MEXP-399 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse bone marrow macrophages from IL-6-/- and IL-10-/- mutants treated with IL-10 or IL-6 stimulation in the presence of LPS
IL-10 or IL-6 stimulation of control 129xC57BL/6 murine bone marrow derived macrophages in the presence of LPS. We used microarrays to detail the global programme of gene expression changes in response to IL-6 or IL-10 stimulation in the presence of lipopolysaccharide. BMDMs were isolated from cont...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5589 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of FNR transcriptional regulator and NarP response regulator knock-out strains of Neisseria gonorrhoeae
Knock out mutants of FNR transcriptional regulator (NGO1579) and NarP response regulator (NGO0752) in N. gonorrhoeae compared to parent strain grown in liquid culture.
ORGANISM(S): Neisseria gonorrhoeae 
2006-08-15 | E-MEXP-726 | biostudies-arrayexpress
TranscriptomicsLNCaP EMETINE TIME COURSE
LNCaP prostate cancer cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treate...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1488 | biostudies-arrayexpress
TranscriptomicsGM00156 EMETINE TIME COURSE
GM00156 (Coriell) cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treated an...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1490 | biostudies-arrayexpress
TranscriptomicsPC3 EMETINE TIME COURSE
PC3 prostate cancer cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treated ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1489 | biostudies-arrayexpress
ProteomicsMechanisms of chlorate toxicity and resistance in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen known to cause both acute and chronic infections. P. aeruginosa often encounters hypoxic/anoxic environments within the host, which increases its tolerance to many conventional antibiotics. Towards identifying novel therapeutic treatments, we have ...
ORGANISM(S): Pseudomonas aeruginosa (strain UCBPP-PA14) 
2023-10-24 | PXD033396 | Pride
Resistance Chlorate toxicity Pseudomonas aeruginosa 
TranscriptomicsTranscriptional profiling of a slyA mutant and a slyA-overexpression strain of Escherichia coli MG1655 in order to elucidate the SlyA regulon
A microarray study was performed to identify the Escherichia coli SlyA regulon. The wild-type (parental) Escherichia coli MG1655 strain was compared to an isogenic slyA deletion mutant, whilst a slyA-overexpression strain (in pET28a) was compared to an empty (pET28a) vector control. Continuous chemo...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2017-01-25 | E-MTAB-5220 | biostudies-arrayexpress
ProteomicsDefining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction
Increasing evidence indicates CD4+ T cells can recognize cancer-specific antigens and control tumor growth. However, it remains difficult to predict the antigens that will be presented by human leukocyte antigen class II molecules (HLA-II) - hindering efforts to optimally target them therapeutically...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-18 | MSV000083991 | MassIVE
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