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TranscriptomicsNovel Regulators of Fgf23 Expression and Mineralization in Hyp Bone
We used gene array analysis of cortical bone to identify Phex-dependent gene transcripts regulating Fgf23 production and mineralization in Hyp mice. We discovered that activation of Fgf receptor- and Wnt-pathways contribute to increased Ffg23 gene transcription in Hyp bone. We found evidence in Hyp ...
ORGANISM(S): Mus musculus 
2009-12-21 | E-GEOD-14242 | biostudies-arrayexpress
TranscriptomicsGPM6B regulates osteoblast differentiation and induction of mineralization by controlling cytoskeleton and matrix vesicle release.
Analysis of GPM6B silenced osteogenic hMSC at gene expression level. Analysis is showing significant changes in genes involved in cytoskeleton organization and biogenesis. Immunocytochemistry confirms changed distribution of actin filaments and change in shape and in size of focal adhesions upon GP...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-26004 | biostudies-arrayexpress
MetabolomicsLC-MS metabolic profiling of mouse plasma and cell culture medium in relation to ABCC6 expression
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disease characterized by progressive ectopic mineralization of the skin, eyes and arteries, for which no effective treatment exists. PXE is caused by inactivating mutations in the gene encoding ABCC6 (MRP6), an ATP-dependent efflux transporter...
2013-11-14 | MTBLS61 | MetaboLights
TranscriptomicsComparison of Mineralizing Synchronous UMR106-01 cells with UMR106-01 cells treated with Mineralization Inhibitor AEBSF
UMR106-01 osteoblastic cells are a model for studying bone mineralization. We have shown that mineralization is temporally synchronized within cultures grown under defined conditions . Cells are plated at time zero and differentiate into osteoblastic phenotype by 64 h later. If an exogenous phosp...
ORGANISM(S): Rattus norvegicus 
2010-11-13 | E-GEOD-21476 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profile of gilthead seabream mineralization-induced VSa16 cells against controls
In the present study, the Agilent-016251 Sparus aurata oligo microarray platform (GEO accession: GPL6467) was used to compare expression profiles of mineralization-induced VSa16 cell cultures against untreated ones. ECM mineralization was induced for 4 weeks by supplementing medium with 50 µg/ml of ...
ORGANISM(S): Sparus aurata 
2011-06-01 | E-GEOD-18941 | biostudies-arrayexpress
ProteomicsA Diecast Mineralization Process Forms the Tough Mantis Shrimp Dactyl Club
Biomineralization, the process by which mineralized tissues grow and harden via biogenic mineral deposition, is a relatively lengthy process in many mineral-producing organisms,resulting in challenges to study the growth and biomineralization of complex hard mineralized tissues. ...
ORGANISM(S): Cellular Organisms 
2019-03-20 | PXD013153 | JPOST Repository
GenomicsLef1 Ablation Alleviates Cartilage Mineralization during Post-traumatic Osteoarthritis
Lef1 Ablation Alleviates Cartilage Mineralization during Post-traumatic Osteoarthritis
PRJNA824872 | ENA
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Osteoblast Mineralization Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of Osteoblast Mineralization Transcriptomes
PRJNA623508 | ENA
TranscriptomicsLef1 Ablation Alleviates Cartilage Mineralization during Post-traumatic Osteoarthritis
Cartilage mineralization is a tightly controlled process, imperative for skeletal growth and fracture repair. However, in osteoarthritis (OA), cartilage mineralization may impact the joint range of motion, inflict pain and may increase chances for joint effusion. Here we attempt to understand the li...
ORGANISM(S): Mus musculus 
2022-05-16 | GSE200522 | GEO
GenomicsCates Soil Carbon Mineralization 16S Amplicon Analysis
Cates Soil Carbon Mineralization 16S Amplicon Analysis Raw sequence reads
PRJNA517141 | ENA
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