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TranscriptomicsTranscription profiling of human patients with chronic kidney disease
Several reports have focused on the identification of biological elements involved in the development of abnormal systemic biochemical alterations in chronic kidney disease, but this abundant literature results most of the time fragmented. To better define the cellular machinery associated to this c...
ORGANISM(S): Homo sapiens 
2009-12-04 | E-GEOD-15072 | biostudies-arrayexpress
TranscriptomicsEffect of Mycophenolic Acid on renal transplant recipients
Mycophenolic acid (MPA), an immunosuppressive drug widely used in kidney transplantation, has been suggested to have anti-fibrotic effects. To analyze at a genomic level these effects, we prospectively studied a group of stable kidney transplant recipients (n=35) on cyclosporine (CyA) and azathiopri...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-14630 | biostudies-arrayexpress
TranscriptomicsA SUMOylated C-terminus fragment of glutamate transporter EAAT2 linked to inherited ALS mediates motor axon impairment
Downregulation of expression and activity levels of the astroglial glutamate transporter EAAT2 is thought to be implicated in motor neuron excitotoxicity in amyotrophic lateral sclerosis (ALS). We previously reported that EAAT2 is cleaved by caspase-3 at the cytosolic C-terminus domain, impairing th...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-26070 | biostudies-arrayexpress
ProteomicsIdentification of immunoreactive proteins of Mycobacterium avium subsp. Paratuberculosis
Mycobacterium avium subsp. paratuberculosis (MAP) is the cause of a chronic enteritis of ruminants (bovine paratuberculosis-Johne disease) that is associated with enormous worldwide economic losses for the zootechnical industries. Diagnosis is based on observation of clinical signs, on the detection...
ORGANISM(S): Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) Other Actinobacteria (class) 
2014-11-20 | PXD001159 | Pride
Mycobacterium avium subsp. paratuberculosis  johne’s disease  immunoreactive proteins  soil biological contaminant 
TranscriptomicsRNA-seq analysis of Pseudomonas syringae pv. tomato DC3000
This experiment analyses the expresssion data of the wild type P. syringae pv. tomato DC3000 compared with its fleQ mutant grown under two different conditions: liquid culture in minimal medium and swarming plates.
ORGANISM(S): Pseudomonas syringae pv. tomato str. DC3000 
2015-12-31 | E-MTAB-3779 | biostudies-arrayexpress
UnknownThe superficial white matter in Alzheimer's disease.
Not available
S-EPMC5125444 | biostudies-literature
TranscriptomicsDevelopmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus
A key event in the pathogenic process of prion diseases is the conversion of the cellular prion protein (PrPC) to an abnormal and protease-resistant isoform (PrPSc). Mice lacking PrP are resistant to prion infection, and down-regulation of PrPC during prion infection prevents neuronal loss and the p...
ORGANISM(S): Mus musculus 
2011-04-12 | E-GEOD-21718 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse FACS purified cortical projection neurons
3 subtypes of cortical projection neurons were purified by fluorescence-activated cell sorting at 4 different stages of development from mouse cortex. A detailed description of the data set is described in Arlotta, P et al (2005)
ORGANISM(S): Mus musculus 
2007-11-20 | E-GEOD-2039 | biostudies-arrayexpress
TranscriptomicsExpression data of hepatic iNKT cells from pLck-hCD1d transgenic mice
CD1d expression by thymocytes is required to select iNKT cells. When CD1d is expressed only on thymocytes (pLck-CD1d tg mice), iNKT cells are hyperresponsive to antigen stimulation suggesting that, in physiological conditions, these cells undergo functional education mediated by additional CD1d-expr...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-42835 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of peripheral blood mononuclear cells before and after eradication of Hepatitis C virus by DAAs
Remarkable improvements in the treatment of HCV infection have been observed since the availability of HCV Direct-antiviral agents (DAAs). We evaluated by microarray the transcriptomic profile of circulating mononuclear cells from 8 chronic HCV patients at baseline and 12 weeks after the end of 4 w...
ORGANISM(S): Homo sapiens 
2023-07-31 | E-MTAB-10952 | biostudies-arrayexpress
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